Functional Foods Research Group, University of Southern Queensland, Toowoomba, QLD 4350, Australia.
Centre for Marine Science and Innovation, School of Biological, Earth and Environmental Sciences, University of New South Wales, Sydney, NSW 2052, Australia.
Nutrients. 2021 Nov 9;13(11):3991. doi: 10.3390/nu13113991.
The microalgal genus has broad applicability to produce biofuels, animal feed supplements and other value-added products including proteins, carotenoids and lipids. This study investigated a potential role of in the reversal of metabolic syndrome. Male Wistar rats ( = 48) were divided into four groups in a 16-week protocol. Two groups were fed either corn starch or high-carbohydrate, high-fat diets (C and H, respectively) for the full 16 weeks. The other two groups received C and H diets for eight weeks and then received 5% freeze-dried in these diets for the final eight weeks (CN and HN, respectively) of the protocol. The H diet was high in fructose and sucrose, together with increased saturated and fats. H rats developed obesity, hypertension, dyslipidaemia, fatty liver disease and left ventricular fibrosis. increased lean mass in CN and HN rats, possibly due to the increased protein intake, and decreased fat mass in HN rats. Intervention with did not change cardiovascular, liver and metabolic parameters or gut structure. The relative abundance of Oxyphotobacteria in the gut microbiota was increased. may be an effective functional food against metabolic syndrome as a sustainable protein source.
该微藻属具有广泛的适用性，可以生产生物燃料、动物饲料补充剂和其他增值产品，包括蛋白质、类胡萝卜素和脂质。本研究探讨了在代谢综合征逆转中的作用。雄性 Wistar 大鼠（n=48）在 16 周方案中分为四组。两组分别用玉米淀粉或高碳水化合物、高脂肪饮食（分别为 C 和 H）喂养 16 周。另外两组先接受 C 和 H 饮食 8 周，然后在饮食中添加 5%的冷冻干燥，在协议的最后 8 周（分别为 CN 和 HN）。H 饮食中果糖和蔗糖含量高，同时饱和脂肪和反式脂肪增加。H 组大鼠出现肥胖、高血压、血脂异常、脂肪肝和左心室纤维化。在 CN 和 HN 组中，增加了瘦体重，可能是由于蛋白质摄入增加，而 HN 组的脂肪量减少。用干预措施并未改变心血管、肝脏和代谢参数或肠道结构。肠道微生物群中 Oxyphotobacteria 的相对丰度增加。可能是一种有效的功能性食品，作为可持续的蛋白质来源，对抗代谢综合征。
