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阿根廷布宜诺斯艾利斯省某区针对 SARS-CoV-2 开展主动监测和缓解的公共卫生干预措施的影响:一项描述性流行病学研究。

Impact of a public health intervention for active surveillance and mitigation of SARS-CoV-2 in a district from Buenos Aires province, Argentina: a descriptive epidemiological study.

机构信息

Mundo Sano Foundation, Buenos Aires, Argentina.

Association for Regional Health Development (ADESAR), San Antonio de Areco, Buenos Aires, Argentina.

出版信息

BMJ Open. 2021 Nov 26;11(11):e053595. doi: 10.1136/bmjopen-2021-053595.

DOI:10.1136/bmjopen-2021-053595
PMID:34836906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8628114/
Abstract

BACKGROUND

The first case of SARS-CoV-2 was reported in Argentina on 3 March 2020. Measures to limit the spread of the virus were implemented, including complete lockdown (26 March). Nonetheless, the virus spread throughout the country, with a first peak of almost a million cases in October. On 30 November, the government's recommendation switched from social, preventive and compulsory isolation, to social, preventive and compulsory distancing.

OBJECTIVES

To describe a tailored public health strategy to mitigate the spread of SARS-CoV-2 and determine its behaviour in San Antonio de Areco district from Buenos Aires province (Argentina) through a private-public association.

DESIGN, SETTING AND PARTICIPANTS: Surveillance of the virus was performed with the local healthcare system, through early identification of cases and the systematic study of each infected individual and contact, regardless of symptomatology, using telemedicine and a COVID-19-specific outpatient clinic. Real-time PCR was used for detection using both individual and pooled samples, with a 12-hour turnaround time.

RESULTS

Up to 30 November, a total of 2426 suspected cases were analysed and 578 were confirmed. Surveillance of health personnel and at-risk populations proved effective, mitigating viral spread. Pooling samples allowed reduction of operator time, helped reduce costs, and allowed detection of both symptomatic and asymptomatic cases.

CONCLUSION

After 8 months of protocol implementation, the strategy to intensively survey groups at higher epidemiological risk and the systematic search for asymptomatic cases with the incorporation of pooled PCR for diagnosis, in combination with individual testing, is an efficient and viable option in populations with similar characteristics, in the frame of social isolation.

摘要

背景

2020 年 3 月 3 日,阿根廷报告了首例 SARS-CoV-2 病例。为了限制病毒的传播,采取了包括全面封锁(3 月 26 日)在内的措施。然而,病毒还是在全国范围内传播,10 月出现了近 100 万例的第一波高峰。11 月 30 日,政府的建议从社会、预防和强制隔离转变为社会、预防和强制隔离。

目的

描述一种针对 SARS-CoV-2 的公共卫生策略,以减轻其传播,并通过公私合作,确定布宜诺斯艾利斯省圣安东尼奥德阿雷科区的疫情行为。

设计、地点和参与者:通过当地医疗保健系统进行病毒监测,通过早期发现病例,并对每个感染个体和接触者进行系统研究,无论是否有症状,均使用远程医疗和专门的 COVID-19 门诊,来确定其行为。使用实时 PCR 进行检测,既可以使用个体样本,也可以使用混合样本,周转时间为 12 小时。

结果

截至 11 月 30 日,共分析了 2426 例疑似病例,确诊了 578 例。对卫生人员和高危人群的监测是有效的,减轻了病毒的传播。混合样本的使用减少了操作人员的时间,有助于降低成本,并能检测出有症状和无症状的病例。

结论

在实施该方案 8 个月后,对高流行病学风险群体进行强化监测的策略,以及系统地寻找无症状病例并结合混合 PCR 进行诊断,与个体检测相结合,在具有类似特征的人群中,在社会隔离的框架下,是一种有效可行的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ea1/8628114/951d3a404f66/bmjopen-2021-053595f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ea1/8628114/a90cae712ff3/bmjopen-2021-053595f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ea1/8628114/951d3a404f66/bmjopen-2021-053595f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ea1/8628114/a90cae712ff3/bmjopen-2021-053595f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ea1/8628114/951d3a404f66/bmjopen-2021-053595f03.jpg

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