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(11; 14) translocation in three boys with acute lymphoblastic leukemia of T-cell immunophenotype.

作者信息

Harbott J, Engel R, Gerein V, Schwamborn D, Rudolph R, Lampert F

出版信息

Blut. 1986 Jan;52(1):45-50. doi: 10.1007/BF00320141.

DOI:10.1007/BF00320141
PMID:3484645
Abstract

Three boys, 12, 15 and 5 years old are presented with acute lymphoblastic leukemia resp. Non-Hodgkin's lymphoma with leukemic transformation. Blast cells could be characterized as being of T-cell origin. Hand mirror variant was the predominant morphologic feature of the blast cells in two patients. Chromosome analysis of the leukemic blast cells revealed a pseudodiploid (modal chromosome number = 46) karyotype in two patients and a pseudotetraploid (modal chromosome number = 92) in one patient. A chromosome translocation (11; 14) with breakpoints at (p 13; q 13) (within the human T-cell receptor alpha chain locus!) was found in the leukemic cells of all three cases plus an additional t (7; 9) (q 22; p 13) in one patient.

摘要

相似文献

1
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引用本文的文献

1
Acute leukemia with chromosome translocation (4;11): 7 new patients and analysis of 71 cases.
Blut. 1987 Jun;54(6):325-35. doi: 10.1007/BF00626012.
2
The mechanism of chromosomal translocation t(11;14) involving the T-cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15.涉及人类染色体14q11上的T细胞受体Cδ基因座和染色体11p15转录区域的染色体易位t(11;14)的机制
EMBO J. 1988 Feb;7(2):385-94. doi: 10.1002/j.1460-2075.1988.tb02825.x.
3
T-cell acute childhood lymphoblastic leukemia with chromosome 14 q 11 anomaly: a morphologic, immunologic, and cytogenetic analysis of 10 patients.伴有14号染色体q11异常的儿童T细胞急性淋巴细胞白血病：10例患者的形态学、免疫学及细胞遗传学分析

本文引用的文献

1
The role of gene dosage and genetic transpositions in carcinogenesis.基因剂量和基因转座在致癌作用中的作用。
Nature. 1981 Nov 26;294(5839):313-8. doi: 10.1038/294313a0.
2
Correlation of karyotype with clinical features in acute lymphoblastic leukemia.急性淋巴细胞白血病核型与临床特征的相关性
Cancer Res. 1982 Jul;42(7):2918-29.
3
All patients with acute nonlymphocytic leukemia may have a chromosomal defect.所有急性非淋巴细胞白血病患者可能都有染色体缺陷。
Blut. 1988 Mar;56(3):117-23. doi: 10.1007/BF00320016.
4
Genetic and cytogenetic changes in acute lymphoblastic leukemia.急性淋巴细胞白血病的遗传和细胞遗传学改变
Med Oncol Tumor Pharmacother. 1988;5(4):211-22. doi: 10.1007/BF03003187.
5
Molecular cloning of the translocation breakpoint in T-ALL 11;14 (p13;q11): genomic map of TCR alpha and delta region on chromosome 14q11 and long-range map of region 11p13.T 细胞急性淋巴细胞白血病中 11;14（p13;q11）易位断点的分子克隆：14q11 上 TCRα和δ区域的基因组图谱以及 11p13 区域的长程图谱。
Hum Genet. 1989 Jun;82(3):264-70. doi: 10.1007/BF00291167.
N Engl J Med. 1981 Jul 16;305(3):135-9. doi: 10.1056/NEJM198107163050304.
4
Inversion of chromosome 14 marks human T-cell chronic lymphocytic leukaemia.14号染色体倒位标志着人类T细胞慢性淋巴细胞白血病。
Nature. 1984;308(5962):858-60. doi: 10.1038/308858a0.
5
Cytogenetic studies on patients with chronic T cell leukemia/lymphoma.慢性T细胞白血病/淋巴瘤患者的细胞遗传学研究。
Blood. 1984 May;63(5):1028-38.
6
New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia.新的染色体易位与儿童急性淋巴细胞白血病的特定免疫表型相关。
Cell. 1984 Jan;36(1):101-9. doi: 10.1016/0092-8674(84)90078-3.
7
A possible subgroup of ALL with 9p-.一种可能的伴有9号染色体短臂缺失的急性淋巴细胞白血病亚组。
Cancer Genet Cytogenet. 1983 Aug;9(4):383-5. doi: 10.1016/0165-4608(83)90086-9.
8
[BFM study 1981/83 of the treatment of highly malignant non-Hodgkin's lymphoma in children: results of therapy stratified according to histologic immunological type and clinical stage].[1981/83年BFM儿童高度恶性非霍奇金淋巴瘤治疗研究：根据组织学免疫类型和临床分期分层的治疗结果]
Klin Padiatr. 1984 May-Jun;196(3):135-42. doi: 10.1055/s-2007-1025596.
9
Common region on chromosome 14 in T-cell leukemia and lymphoma.T细胞白血病和淋巴瘤中14号染色体上的共同区域。
Science. 1984 Dec 21;226(4681):1445-7. doi: 10.1126/science.6438800.
10
Oncogenes: clues to carcinogenesis.癌基因：致癌作用的线索
Eur J Pediatr. 1984 Jan;141(3):134-42. doi: 10.1007/BF00443210.