用于动脉粥样硬化靶向治疗的纳米技术
Nanotechnology for Targeted Therapy of Atherosclerosis.
作者信息
Hossaini Nasr Seyedmehdi, Huang Xuefei
机构信息
Department of Chemistry, Michigan State University, East Lansing, MI, United States.
Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, United States.
出版信息
Front Pharmacol. 2021 Nov 12;12:755569. doi: 10.3389/fphar.2021.755569. eCollection 2021.
Atherosclerosis is the major cause of heart attack and stroke that are the leading causes of death in the world. Nanomedicine is a powerful tool that can be engineered to target atherosclerotic plaques for therapeutic and diagnosis purposes. In this review, advances in designing nanoparticles with therapeutic effects on atherosclerotic plaques known as atheroprotective nanomedicine have been summarized to stimulate further development and future translation.
动脉粥样硬化是心脏病发作和中风的主要原因，而心脏病发作和中风是全球主要的死亡原因。纳米医学是一种强大的工具，可设计用于靶向动脉粥样硬化斑块以进行治疗和诊断。在本综述中，总结了在设计对动脉粥样硬化斑块具有治疗作用的纳米颗粒（即动脉粥样硬化保护纳米医学）方面的进展，以促进进一步的发展和未来的转化应用。
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