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辉瑞-生物科技 COVID-19 疫苗接种后新发巨细胞动脉炎。

New-onset Polymyalgia Rheumatica Following the Administration of the Pfizer-BioNTech COVID-19 Vaccine.

机构信息

Division of Rheumatology, National Hospital Organization Disaster Medical Center, Japan.

Division of Cardiology, National Hospital Organization Disaster Medical Center, Japan.

出版信息

Intern Med. 2022 Mar 1;61(5):749-753. doi: 10.2169/internalmedicine.8651-21. Epub 2021 Dec 11.

Abstract

We herein report the case of an 80-year-old Japanese woman who presented to our hospital with bilateral pain in the shoulders and hips lasting for a month since 2 days after the second dose of the BNT162b2 COVID-19 vaccine. Her physical findings, laboratory data, and ultrasonographic findings of bilateral biceps tenosynovitis and lateral subacromial bursitis were consistent with a diagnosis of polymyalgia rheumatica (PMR). She was successfully treated with oral prednisolone 15 mg/day. Although a causal relationship could not be definitively confirmed, PMR should be considered as a differential diagnosis in cases of persistent myalgia after administration of the BNT162b2 vaccine.

摘要

我们在此报告一例 80 岁日本女性病例,她在第二次接种 BNT162b2 COVID-19 疫苗后 2 天出现双肩和髋关节双侧疼痛,持续 1 个月。她的体格检查、实验室数据和双侧肱二头肌腱鞘炎和肩峰下滑囊炎的超声检查结果与巨细胞性多肌痛(PMR)的诊断一致。她接受了 15 毫克/天的口服泼尼松龙治疗,病情得到了成功缓解。尽管不能明确确定因果关系,但在接种 BNT162b2 疫苗后持续出现肌痛的情况下,应考虑 PMR 作为鉴别诊断。

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