Grounds R M, Moore M, Morgan M
Eur J Anaesthesiol. 1986 Jan;3(1):11-7.
The relative potencies of the intravenous anaesthetics propofol and thiopentone have been investigated by finding the dose necessary to produce unconsciousness in approximately 30%, 50% and 80% of patients. The estimated potency of propofol to thiopentone was 1:1.604 as obtained by the probit method of analysis which estimates the logarithm of the relative potency.
通过确定使约30%、50%和80%的患者产生意识丧失所需的剂量,对静脉麻醉药丙泊酚和硫喷妥钠的相对效价进行了研究。通过分析的概率单位法估计相对效价的对数,得出丙泊酚与硫喷妥钠的估计效价为1:1.604。