Program in Human Nutrition, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Pediatric Hypertension Program, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Pediatr Res. 2022 Sep;92(3):853-861. doi: 10.1038/s41390-021-01893-w. Epub 2021 Dec 16.
The Reversing the Negative cardiovascular Effects on Weight (ReNEW) Clinic is a prospective cohort study in children and adolescents (≤21 years) at the Johns Hopkins Children's Center.
Cross-sectional analysis between diet quality using the Alternative Healthy Eating Index (AHEI-2010), pro-inflammatory potential using the Children's Dietary Inflammatory Index (C-DII), and cardiometabolic outcomes. AHEI-2010 and C-DII scores were assessed by median intake determined from the sample distribution and associated with cardiometabolic measures using linear regression models. Changes in measures were evaluated in a sub-sample of participants invited to attend follow-up visits due to the presence of hypertensive blood pressure (n = 33).
Participants (n = 90) reported an average energy intake of 1790 kcal/day (SD ± 734), AHEI-2010 score of 55.04 (SD ± 9.86) (range: 0 to 110) and C-DII score of -0.12 (±0.86) (range -5 to 5). Participants with higher quality/anti-inflammatory diets trended towards more favorable cardiometabolic measures at baseline. Among the sub-sample (n = 33), there was a significant reduction in total energy (m = -302 kcal/day; p-value= 0.03) but no change in AHEI-2010 (p-value = 0.73) or C-DII score (p-value = 0.85) over follow-up.
Despite stable diet quality scores, outpatient dietary and behavioral counseling may be an effective tool to reduce energy intake in youth with overweight/obesity and elevated blood pressure.
Diet quality scores among obese, hypertensive, African American adolescents were low and reflect a pro-inflammatory diet. Reported intake was negligible for fruits, whole grains, nuts, and legumes, and well above the daily limit for sodium and saturated fat. Participants with high quality/anti-inflammatory diet quality scores trended toward improved cardiometabolic measures. Outpatient dietary counseling resulted in reduced total energy intake.
约翰霍普金斯儿童中心的 Reversing the Negative cardiovascular Effects on Weight (ReNEW) 诊所是一项针对儿童和青少年（≤21 岁）的前瞻性队列研究。
使用替代健康饮食指数（AHEI-2010）评估饮食质量，使用儿童饮食炎症指数（C-DII）评估促炎潜能，并评估两者与心脏代谢结局的关系。AHEI-2010 和 C-DII 评分通过样本分布确定的中位数摄入进行评估，并使用线性回归模型与心脏代谢测量值相关联。在由于高血压血压而被邀请参加随访的参与者的子样本中评估了测量值的变化（n=33）。
参与者（n=90）报告平均能量摄入量为 1790 千卡/天（SD±734），AHEI-2010 评分为 55.04（SD±9.86）（范围：0 至 110），C-DII 评分为-0.12（±0.86）（范围-5 至 5）。饮食质量更高/抗炎的参与者在基线时的心脏代谢指标更有利。在子样本（n=33）中，总能量显著减少（m=-302 千卡/天；p 值=0.03），但 AHEI-2010（p 值=0.73）或 C-DII 评分（p 值=0.85）在随访期间没有变化。
尽管饮食质量评分稳定，但门诊饮食和行为咨询可能是一种有效的工具，可以减少超重/肥胖和高血压青少年的能量摄入。
肥胖、高血压、非裔美国青少年的饮食质量评分较低，反映出促炎饮食。报告的摄入量在水果、全谷物、坚果和豆类方面微不足道，而在钠和饱和脂肪方面则远远超过每日限量。饮食质量评分较高/抗炎的参与者心脏代谢指标改善趋势明显。门诊饮食咨询导致总能量摄入减少。
