• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

用于动脉栓塞和实质器官肿瘤热疗的磁性纳米材料：综述

Magnetic Nanomaterials for Arterial Embolization and Hyperthermia of Parenchymal Organs Tumors: A Review.

作者信息

Kazantseva Natalia E, Smolkova Ilona S, Babayan Vladimir, Vilčáková Jarmila, Smolka Petr, Saha Petr

机构信息

Centre of Polymer Systems, Tomas Bata University in Zlín, Třída Tomáše Bati 5678, 760 01 Zlín, Czech Republic.

Polymer Centre, Faculty of Technology, Tomas Bata University in Zlín, Vavrečkova 275, 760 01 Zlín, Czech Republic.

出版信息

Nanomaterials (Basel). 2021 Dec 15;11(12):3402. doi: 10.3390/nano11123402.

DOI:10.3390/nano11123402
PMID:34947751
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8706233/
Abstract

Magnetic hyperthermia (MH), proposed by R. K. Gilchrist in the middle of the last century as local hyperthermia, has nowadays become a recognized method for minimally invasive treatment of oncological diseases in combination with chemotherapy (ChT) and radiotherapy (RT). One type of MH is arterial embolization hyperthermia (AEH), intended for the presurgical treatment of primary inoperable and metastasized solid tumors of parenchymal organs. This method is based on hyperthermia after transcatheter arterial embolization of the tumor's vascular system with a mixture of magnetic particles and embolic agents. An important advantage of AEH lies in the double effect of embolotherapy, which blocks blood flow in the tumor, and MH, which eradicates cancer cells. Consequently, only the tumor undergoes thermal destruction. This review introduces the progress in the development of polymeric magnetic materials for application in AEH.

摘要

磁热疗（MH）由R. K. 吉尔克里斯特于上世纪中叶作为局部热疗提出，如今已成为一种公认的与化疗（ChT）和放疗（RT）联合用于肿瘤疾病微创治疗的方法。磁热疗的一种类型是动脉栓塞热疗（AEH），旨在对实质器官的原发性不可切除和转移性实体瘤进行术前治疗。该方法基于用磁性颗粒和栓塞剂的混合物对肿瘤血管系统进行经导管动脉栓塞后的热疗。动脉栓塞热疗的一个重要优势在于栓塞疗法的双重作用，它能阻断肿瘤内的血流，而磁热疗则能根除癌细胞。因此，只有肿瘤会受到热破坏。本综述介绍了用于动脉栓塞热疗的聚合物磁性材料的开发进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/63903d1397a7/nanomaterials-11-03402-g022.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/014be4e6f8fa/nanomaterials-11-03402-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/558ba8b7f9ba/nanomaterials-11-03402-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/d211f3de4efc/nanomaterials-11-03402-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/ce0fc653a2f8/nanomaterials-11-03402-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/eee81ce23f36/nanomaterials-11-03402-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/08828383c805/nanomaterials-11-03402-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/e8cc7b884749/nanomaterials-11-03402-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/83186795e3e7/nanomaterials-11-03402-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/9e2aa5ce043a/nanomaterials-11-03402-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/280e8bb3d1bb/nanomaterials-11-03402-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/708258f805b2/nanomaterials-11-03402-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/8614f3062d2b/nanomaterials-11-03402-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/1b9caee71fe3/nanomaterials-11-03402-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/e479fc1ae747/nanomaterials-11-03402-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/09b647e0e437/nanomaterials-11-03402-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/4d7873caedb0/nanomaterials-11-03402-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/3a63b88719b1/nanomaterials-11-03402-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/66842f5f0027/nanomaterials-11-03402-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/8bcdc06113b4/nanomaterials-11-03402-g019.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/46901b112f03/nanomaterials-11-03402-g020.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/0b381b7d7a04/nanomaterials-11-03402-g021.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/63903d1397a7/nanomaterials-11-03402-g022.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/014be4e6f8fa/nanomaterials-11-03402-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/558ba8b7f9ba/nanomaterials-11-03402-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/d211f3de4efc/nanomaterials-11-03402-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/ce0fc653a2f8/nanomaterials-11-03402-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/eee81ce23f36/nanomaterials-11-03402-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/08828383c805/nanomaterials-11-03402-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/e8cc7b884749/nanomaterials-11-03402-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/83186795e3e7/nanomaterials-11-03402-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/9e2aa5ce043a/nanomaterials-11-03402-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/280e8bb3d1bb/nanomaterials-11-03402-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/708258f805b2/nanomaterials-11-03402-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/8614f3062d2b/nanomaterials-11-03402-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/1b9caee71fe3/nanomaterials-11-03402-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/e479fc1ae747/nanomaterials-11-03402-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/09b647e0e437/nanomaterials-11-03402-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/4d7873caedb0/nanomaterials-11-03402-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/3a63b88719b1/nanomaterials-11-03402-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/66842f5f0027/nanomaterials-11-03402-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/8bcdc06113b4/nanomaterials-11-03402-g019.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/46901b112f03/nanomaterials-11-03402-g020.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/0b381b7d7a04/nanomaterials-11-03402-g021.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5413/8706233/63903d1397a7/nanomaterials-11-03402-g022.jpg

相似文献

1
Magnetic Nanomaterials for Arterial Embolization and Hyperthermia of Parenchymal Organs Tumors: A Review.用于动脉栓塞和实质器官肿瘤热疗的磁性纳米材料：综述
Nanomaterials (Basel). 2021 Dec 15;11(12):3402. doi: 10.3390/nano11123402.
2
Arterial embolization hyperthermia using As2O3 nanoparticles in VX2 carcinoma-induced liver tumors.使用 As2O3 纳米粒子进行动脉栓塞热疗治疗 VX2 诱导的肝癌肿瘤。
PLoS One. 2011 Mar 23;6(3):e17926. doi: 10.1371/journal.pone.0017926.
3
Tumor response to arterial embolization hyperthermia and direct injection hyperthermia in a rabbit liver tumor model.兔肝肿瘤模型中肿瘤对动脉栓塞热疗和直接注射热疗的反应。
J Surg Oncol. 2002 Jul;80(3):149-56. doi: 10.1002/jso.10118.
4
Phase-Transitional Bismuth-Based Metals enable Rapid Embolotherapy, Hyperthermia, and Biomedical Imaging.相变铋基金属可实现快速栓塞治疗、热疗和生物医学成像。
Adv Mater. 2022 Oct;34(42):e2205002. doi: 10.1002/adma.202205002. Epub 2022 Sep 18.
5
Method for Ferrite Nanomaterials-Mediated Cellular Magnetic Hyperthermia.铁氧体纳米材料介导的细胞磁热疗方法
ACS Biomater Sci Eng. 2020 Dec 14;6(12):6652-6660. doi: 10.1021/acsbiomaterials.0c01443. Epub 2020 Nov 18.
6
Selective induction hyperthermia following transcatheter arterial embolization with a mixture of nano-sized magnetic particles (ferucarbotran) and embolic materials: feasibility study in rabbits.经导管动脉栓塞术联合纳米级磁性颗粒（ferucarbotran）与栓塞材料后进行选择性诱导热疗：兔可行性研究
Radiat Med. 2008 May;26(4):179-87. doi: 10.1007/s11604-007-0212-9. Epub 2008 May 29.
7
Maghemite based silicone composite for arterial embolization hyperthermia.用于动脉栓塞热疗的基于磁赤铁矿的硅酮复合材料。
Mater Sci Eng C Mater Biol Appl. 2015 Mar;48:632-41. doi: 10.1016/j.msec.2014.12.046. Epub 2014 Dec 19.
8
Transcatheter arterial embolization in the trauma patient: a review.创伤患者的经导管动脉栓塞术：综述
Semin Intervent Radiol. 2004 Mar;21(1):11-22. doi: 10.1055/s-2004-831401.
9
Optimization Study on Specific Loss Power in Superparamagnetic Hyperthermia with Magnetite Nanoparticles for High Efficiency in Alternative Cancer Therapy.基于磁铁矿纳米颗粒的超顺磁性热疗中比损耗功率的优化研究，以实现替代癌症治疗的高效性
Nanomaterials (Basel). 2020 Dec 26;11(1):40. doi: 10.3390/nano11010040.
10
Magnetically mediated hyperthermia: current status and future directions.磁介导热疗：现状与未来方向。
Int J Hyperthermia. 2002 Jul-Aug;18(4):267-84. doi: 10.1080/02656730110108785.

引用本文的文献

1
Magneto-responsive hyaluronan hydrogel for hyperthermia and bioprinting: Magnetic, rheological properties and biocompatibility.用于热疗和生物打印的磁响应性透明质酸水凝胶：磁性、流变学性质及生物相容性
APL Bioeng. 2023 Sep 7;7(3):036113. doi: 10.1063/5.0147181. eCollection 2023 Sep.
2
Au-Coated Superparamagnetic Iron Oxide Nanoparticles for Dual Magnetic Hyperthermia and Radionuclide Therapy of Hepatocellular Carcinoma.载金-钴核壳结构超顺磁性氧化铁纳米粒子用于肝癌的双重磁热疗与放射性核素治疗
Int J Mol Sci. 2023 Mar 9;24(6):5282. doi: 10.3390/ijms24065282.
3
Nano drugs delivery system: A novel promise for the treatment of atrial fibrillation.

本文引用的文献

1
Nanoparticle Size Threshold for Magnetic Agglomeration and Associated Hyperthermia Performance.磁团聚及相关热疗性能的纳米颗粒尺寸阈值
Nanomaterials (Basel). 2021 Oct 21;11(11):2786. doi: 10.3390/nano11112786.
2
Challenges and recommendations for magnetic hyperthermia characterization measurements.磁热疗特性测量的挑战与建议。
Int J Hyperthermia. 2021;38(1):447-460. doi: 10.1080/02656736.2021.1892837.
3
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.
纳米药物递送系统：治疗心房颤动的新希望。
Front Cardiovasc Med. 2022 Oct 26;9:906350. doi: 10.3389/fcvm.2022.906350. eCollection 2022.
4
The Advances and Biomedical Applications of Imageable Nanomaterials.可成像纳米材料的进展与生物医学应用
Front Bioeng Biotechnol. 2022 Jul 5;10:914105. doi: 10.3389/fbioe.2022.914105. eCollection 2022.
5
Unidirectional Magnetic Anisotropy in Molybdenum Dioxide-Hematite Mixed-Oxide Nanostructures.二氧化钼-赤铁矿混合氧化物纳米结构中的单向磁各向异性
Nanomaterials (Basel). 2022 Mar 12;12(6):938. doi: 10.3390/nano12060938.
《全球癌症统计数据 2020：全球 185 个国家和地区 36 种癌症的发病率和死亡率估计》。
CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.
4
magnetic nanoparticle hyperthermia: a review on preclinical studies, low-field nano-heaters, noninvasive thermometry and computer simulations for treatment planning.磁性纳米颗粒热疗：临床前研究、低场纳米发热体、无创测温及治疗计划计算机模拟的综述。
Int J Hyperthermia. 2020 Dec;37(3):76-99. doi: 10.1080/02656736.2020.1800831.
5
Second-look surgery plus hyperthermic intraperitoneal chemotherapy versus surveillance in patients at high risk of developing colorectal peritoneal metastases (PROPHYLOCHIP-PRODIGE 15): a randomised, phase 3 study.二期手术加腹腔内热灌注化疗与监测在有发生结直肠腹膜转移高危患者中的对比（PROPHYLOCHIP-PRODIGE 15）：一项随机、3 期研究。
Lancet Oncol. 2020 Sep;21(9):1147-1154. doi: 10.1016/S1470-2045(20)30322-3. Epub 2020 Jul 24.
6
A review on numerical modeling for magnetic nanoparticle hyperthermia: Progress and challenges.磁纳米粒子热疗的数值建模综述：进展与挑战。
J Therm Biol. 2020 Jul;91:102644. doi: 10.1016/j.jtherbio.2020.102644. Epub 2020 Jun 17.
7
Cancer therapy with iron oxide nanoparticles: Agents of thermal and immune therapies.铁氧化物纳米颗粒的癌症治疗：热疗和免疫治疗的试剂。
Adv Drug Deliv Rev. 2020;163-164:65-83. doi: 10.1016/j.addr.2020.06.025. Epub 2020 Jun 27.
8
Heating technology for malignant tumors: a review.加热技术治疗恶性肿瘤：综述。
Int J Hyperthermia. 2020;37(1):711-741. doi: 10.1080/02656736.2020.1779357.
9
Enhancing the magnetic and inductive heating properties of FeO nanoparticles via morphology control.通过形貌控制增强FeO纳米颗粒的磁性和感应加热性能。
Nanotechnology. 2020 Apr 17;31(27):275706. doi: 10.1088/1361-6528/ab84a3. Epub 2020 Mar 30.
10
Molecular and biological rationale of hyperthermia as radio- and chemosensitizer.作为一种放射增敏剂和化学增敏剂的热疗的分子和生物学基础。
Adv Drug Deliv Rev. 2020;163-164:84-97. doi: 10.1016/j.addr.2020.01.003. Epub 2020 Jan 23.