CNC-Center for Neurosciences and Cell Biology, Coimbra, Portugal.
FMUC-Faculty of Medicine-University of Coimbra, Coimbra, Portugal.
Curr Top Microbiol Immunol. 2021;432:45-55. doi: 10.1007/978-3-030-83391-6_5.
Since the first description of extracellular vesicles in a filamentous fungus, Alternaria infectoria, data has been gathered showing the importance of EVs in the interaction of filamentous fungi with the environment and with the animal and plant hosts. In Aspergillus spp. it was described paracrine effects over host cells, namely regulating the immune response; in phytopathogens, it was described the importance of EVs in infection structures. The study of the filamentous fungi EVs associated with cargos indicates important roles in the breakdown of substrates and the remodeling of the cell wall. Nevertheless, the information about filamentous fungi EVs is still scarce and the biogenesis and release deserve further study.
自丝状真菌（Alternaria infectoria）中首次描述细胞外囊泡以来，已有数据表明 EVs 在丝状真菌与环境以及与动植物宿主相互作用中的重要性。在曲霉属（Aspergillus spp.）中，已描述了对宿主细胞的旁分泌作用，即调节免疫反应；在植物病原菌中，已描述了 EVs 在感染结构中的重要性。与货物相关的丝状真菌 EVs 的研究表明，其在基质分解和细胞壁重塑中发挥着重要作用。然而，关于丝状真菌 EVs 的信息仍然很少，其生物发生和释放仍值得进一步研究。
