Department of Natural Products and Alternative Medicine, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, P.O Box # 1982, Dammam 31441, Kingdom of Saudi Arabia.
Department of Pharmacy, Shaheed Benazir Bhutto University Sheringal Dir Upper Khyber Pakhtun Khwa, Pakistan.
Asian Pac J Cancer Prev. 2022 Jan 2;22(12):3735-3740. doi: 10.31557/APJCP.2021.22.12.3735.
The journal of APJCP (Asian Pacific Journal of Cancer Prevention) focuses to gather relevant and up-to-date novel information's related to cancer sciences. The research methodologies and approaches adopted by the researcher are prone to variation which may be desirable in the context of novel scientific findings however, the reproducibility for these studies needs to be unified and assured. The reproducibility issues are highly concerned when preclinical studies are reported in cancer, for natural products in particular. The natural products and medicinal plants are prone to a wide variation in terms of phytochemistry and phyto-pharmacology, ultimately affecting the end results for cancer studies. Hence the need for specific guidelines to adopt a best-practice in cancer research are utmost essential. The current AIMRDA guidelines aims to develop a consensus-based tool in order to enhance the quality and assure the reproducibility of studies reporting natural products in cancer prevention. A core working committee of the experts developed an initial draft for the guidelines where more focus was kept for the inclusion of specific items not covered in previous published tools. The initial draft was peer-reviewed, experts-views provided, and improved by a scientific committee comprising of field research experts, editorial experts of different journals, and academics working in different organization worldwide. The feedback from continuous online meetings, mail communications, and webinars resulted a final draft in the shape of a checklist tool, covering the best practices related to the field of natural products research in cancer prevention and treatment. It is mandatory for the authors to read and follow the AIMRDA tool, and be aware of the good-practices to be followed in cancer research prior to any submission to APJCP. Though the tool is developed based on experts in the field, it needs to be further updated and validated in practice via implementation in the field.
《亚太癌症预防杂志》（Asian Pacific Journal of Cancer Prevention，APJCP）重点收录与癌症科学相关的最新、相关的创新信息。研究人员采用的研究方法和途径可能会有所不同，这在新的科学发现的背景下是可取的，然而，这些研究的可重复性需要统一和保证。当报告癌症的临床前研究时，特别是对于天然产物，可重复性问题受到高度关注。天然产物和药用植物在植物化学和植物药理学方面容易出现广泛的变化，最终影响癌症研究的最终结果。因此，需要制定具体的指南，以采用癌症研究的最佳实践。目前的 AIMRDA 指南旨在制定一项基于共识的工具，以提高报告癌症预防中天然产物的研究的质量并确保其可重复性。一个由专家组成的核心工作组制定了指南的初步草案，其中更注重纳入以前发表的工具未涵盖的特定项目。初始草案经过同行评审、专家意见提供，并由一个由领域研究专家、不同期刊的编辑专家以及在世界各地不同组织工作的学者组成的科学委员会进行改进。通过持续的在线会议、邮件交流和网络研讨会，提出了最终草案，形成了一个检查表工具，涵盖了癌症预防和治疗领域天然产物研究的最佳实践。作者必须阅读和遵循 AIMRDA 工具，并在向 APJCP 提交任何内容之前，了解癌症研究中要遵循的良好实践。虽然该工具是根据该领域的专家制定的，但需要通过在实践中的实施进一步更新和验证。
