Bernier Charlie, Goetz Coralie, Jubinville Eric, Jean Julie
Department of Food Sciences, Institute of Nutrition and Functional Foods (INAF), Université Laval, Quebec, QC G1V 0A6, Canada.
Foods. 2021 Dec 31;11(1):102. doi: 10.3390/foods11010102.
Due to rising consumer preference for natural remedies, the search for natural antiviral agents has accelerated considerably in recent years. Among the natural sources of compounds with potential antiviral proprieties, berries are interesting candidates, due to their association with health-promoting properties, including antioxidant, antimutagenic, anticancer, antimicrobial, anti-inflammatory, and neuroprotective properties. The past two decades have witnessed a flurry of new findings. Studies suggest promising antiviral proprieties against enveloped and non-enveloped viruses, particularly of cranberries, blueberries, blackcurrants, black raspberries, and pomegranates. The aim of this review is to assemble these findings, to list the implied mechanisms of action, and thereby point out promising subjects for research in this field, in the hope that compounds obtainable from natural sources such as berries may be used someday to treat, or even prevent, viral infections.
由于消费者对天然疗法的偏好日益增加,近年来对天然抗病毒剂的研究显著加速。在具有潜在抗病毒特性的天然化合物来源中,浆果是引人关注的候选者,因为它们具有促进健康的特性,包括抗氧化、抗诱变、抗癌、抗菌、抗炎和神经保护特性。在过去二十年中出现了大量新发现。研究表明,特别是蔓越莓、蓝莓、黑加仑、黑树莓和石榴,对包膜病毒和非包膜病毒具有有前景的抗病毒特性。本综述的目的是汇总这些发现,列出隐含的作用机制,从而指出该领域有前景的研究课题,希望有朝一日从浆果等天然来源获得的化合物可用于治疗甚至预防病毒感染。