Bakri Marina, Lovato Fernanda Christo, Diosti Géssica de Mattos, Salles Yorgos Luiz Santos de Graça, Moreira Paulo Henrique Brites, Collaço Luiz Martins, Czeczko Nicolau Gregori, Malafaia Osvaldo, Kubrusly Luiz Fernando
Institute for Medical Research, Curitiba, PR, Brazil.
Mackenzie Evangelical Faculty of Paraná, Curitiba, PR, Brazil.
Arq Bras Cir Dig. 2022 Jan 5;34(3):e1527. doi: 10.1590/0102-672020200003e1527. eCollection 2022.
The use of polypropylene meshes for surgical repair of the abdominal wall contributes to a reduction of the of recurrence rates of hernias or defects. However, its intra-abdominal use comes along with the formation of adhesions and several complications. The study and the search for alternative materials, including bovine pericardium, have been regarded as an option for the correction and treatment of resulting hernias with better adaptations and effectiveness.
Evaluating the inflammatory process of the bovine pericardium in comparison with the inflammatory process of synthetic polypropylene mesh.
Bovine pericardium mesh and polypropylene mesh were placed, both on the same animal. The first group had the mesh removed for analysis on day 20, and the second group on day 40. The variables congestion, granulation, giant cells, necrosis, acute inflammation, chronic inflammation and collagen were analyzed.
All variables were found in greater numbers as a response to the polypropylene mesh, except for the collagen, which, on day 40, was greater in response to the bovine pericardium mesh.
The data in this study suggest that there is less inflammatory reaction in response to bovine pericardium mesh when compared to polypropylene mesh.
使用聚丙烯网片进行腹壁手术修复有助于降低疝或缺损的复发率。然而，其在腹腔内的使用会伴随粘连形成和多种并发症。对包括牛心包在内的替代材料的研究和探索，被视为以更好的适应性和有效性矫正和治疗由此产生的疝的一种选择。
比较牛心包与合成聚丙烯网片的炎症过程。
将牛心包网片和聚丙烯网片放置在同一只动物身上。第一组在第20天取出网片进行分析，第二组在第40天取出。分析充血、肉芽组织、巨细胞、坏死、急性炎症、慢性炎症和胶原蛋白等变量。
除了胶原蛋白外，所有变量对聚丙烯网片的反应数量更多，而在第40天，胶原蛋白对牛心包网片的反应更多。
本研究数据表明，与聚丙烯网片相比，牛心包网片引起的炎症反应更少。
