用于生物医学应用的细菌纤维素的表面改性。

Ken and Mary Alice Lindquist Department of Nuclear Engineering, Pennsylvania State University, University Park, PA 16802, USA.

Department of Biomedical Engineering, Pennsylvania State University, University Park, PA 16802, USA.

Int J Mol Sci. 2022 Jan 6;23(2):610. doi: 10.3390/ijms23020610.

Bacterial cellulose is a naturally occurring polysaccharide with numerous biomedical applications that range from drug delivery platforms to tissue engineering strategies. BC possesses remarkable biocompatibility, microstructure, and mechanical properties that resemble native human tissues, making it suitable for the replacement of damaged or injured tissues. In this review, we will discuss the structure and mechanical properties of the BC and summarize the techniques used to characterize these properties. We will also discuss the functionalization of BC to yield nanocomposites and the surface modification of BC by plasma and irradiation-based methods to fabricate materials with improved functionalities such as bactericidal capabilities.

细菌纤维素是一种天然存在的多糖，具有许多医学应用，从药物输送平台到组织工程策略。BC 具有出色的生物相容性、微观结构和机械性能，类似于天然人体组织，因此适合替代受损或受伤的组织。在这篇综述中，我们将讨论 BC 的结构和机械性能，并总结用于表征这些性能的技术。我们还将讨论 BC 的功能化以获得纳米复合材料，以及通过等离子体和辐照方法对 BC 的表面改性，以制造具有更好功能的材料，如杀菌能力。