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属的生物多样性:植物化学和药理学天然产物的前景。

The Biodiversity of the Genus : Phytochemical and Pharmacological Natural Products Prospectives.

机构信息

Department of Pharmacognosy, Faculty of Pharmacy, South Valley University, Qena 83523, Egypt.

Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.

出版信息

Molecules. 2022 Jan 20;27(3):672. doi: 10.3390/molecules27030672.

Abstract

Although a broad variety of classes of bioactive compounds have already been isolated from seaweeds of the genus , most different species are still chemically and biologically unexplored. species are well-known brown seaweeds belonging to the Dictyotaceae (Phaeophyta). The phytochemical composition within the genus has recently received considerable interest, and a vast array of components, including diterpenes, sesquiterepenes, sterols, amino acids, as well as saturated and polyunsaturated fatty acids, have been characterized. The contribution of these valued metabolites to the biological potential, which includes anti-proliferative, anti-microbial, antiviral, antioxidant, anti-inflammatory, and anti-hyperpigmentation activities, of the genus has also been explored. Therefore, this is the most comprehensive review, focusing on the published literature relevant to the chemically and pharmacologically diverse biopharmaceuticals isolated from different species of the genus during the period from 1976 to now.

摘要

虽然已经从 属的海藻中分离出了广泛的具有生物活性的化合物类别,但大多数不同的物种在化学和生物学上仍未被探索。 种是属于 (褐藻门)的知名褐藻。属内的植物化学成分最近引起了相当大的关注,并且已经鉴定出了大量的成分,包括二萜、倍半萜、甾醇、氨基酸以及饱和和多不饱和脂肪酸。这些有价值的代谢产物对该属的生物潜力做出了贡献,包括抗增殖、抗微生物、抗病毒、抗氧化、抗炎和抗色素沉着活性。因此,这是最全面的综述,重点介绍了自 1976 年以来从该属的不同物种中分离出的具有化学和药理学多样性的生物制药的相关已发表文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec11/8838102/f7aee7f38db9/molecules-27-00672-g001.jpg

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