Algamar Laboratory, Institute of Biology, Fluminense Federal University, Rua Prof. Frames Waldemar de Freitas Reis, Block M, São Domingos, Niterói 24210-201, RJ, Brazil.
Mar Drugs. 2023 Sep 4;21(9):484. doi: 10.3390/md21090484.
Dictyotaceae algae have gained recognition as prolific producers of diterpenes, which are molecules with significant biotechnological potential. These diterpenes hold immense promise as potential active drug components, making the algae a compelling area of study. The present review aims to present the latest advancements in understanding the biopotential of Brazilian Dictyota and Canistrocarpus brown algae, shedding light on the remarkable diversity and the biological and pharmacological potential of the secondary metabolites they produce. A total of 78 articles featuring 26 distinct diterpenes are reported in this review, with their antiviral potential being the mosthighlighted biological activity. Despite considerable research on these algae and their diterpenes, significant knowledge gaps persist. Consequently, the present review is poised to serve as a pivotal resource for researchers who are actively engaged in the pursuit of active diterpenes beyond the immediate purview. Furthermore, it holds the potential to catalyze an increase in research endeavors centered around these algal species within the geographical confines of the Brazilian coastline. Also, it assumes a critical role in directing future scientific explorations toward a better comprehension of these compounds and their ecological implications.
马尾藻科藻类已被公认为二萜类化合物的丰富生产者，这些化合物具有重要的生物技术潜力。这些二萜类化合物具有成为潜在活性药物成分的巨大潜力，使藻类成为一个引人关注的研究领域。本综述旨在介绍对巴西马尾藻和 Canistrocarpus 褐藻生物潜力的最新理解，阐明它们产生的次生代谢物的显著多样性以及生物和药理学潜力。本综述共报道了 78 篇文章，涉及 26 种不同的二萜类化合物，其中抗病毒活性是最突出的生物活性。尽管对这些藻类及其二萜类化合物进行了大量研究，但仍存在显著的知识空白。因此，本综述有望成为积极从事超越当前研究范围寻找活性二萜类化合物的研究人员的重要资源。此外，它还有潜力促进围绕这些藻类物种在巴西海岸线地理范围内开展更多的研究工作。它还在指导未来的科学探索方面发挥着关键作用，以更好地理解这些化合物及其生态影响。
