Bianchi Serena, Torge Diana, Rinaldi Fabiola, Piattelli Maurizio, Bernardi Sara, Varvara Giuseppe
Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Department of Innovative Technologies in Medicine & Dentistry, University of Chieti-Pescara 'Gabriele d'Annunzio', Via dei Vestini 11, 66100 Chieti, Italy.
Biomedicines. 2022 Jan 20;10(2):218. doi: 10.3390/biomedicines10020218.
Platelets are a cellular subgroup of elements circulating in the bloodstream, responsible for the innate immunity and repairing processes. The diseases affecting this cellular population, depending on the degree, can vary from mild to severe conditions, which have to be taken into consideration in cases of minor dental procedures. Their secretion of growth factors made them useful in the regenerative intervention. The aim of this review is to examine the platelets from biological, examining the biogenesis of the platelets and the biological role in the inflammatory and reparative processes and clinical point of view, through the platelets' pathology and their use as platelets concentrates in dental regenerative surgery.
血小板是血液循环中的一种细胞亚群，负责先天免疫和修复过程。影响这一细胞群体的疾病，根据程度不同，可从轻度到重度，在进行小型牙科手术时必须予以考虑。它们分泌的生长因子使其在再生干预中发挥作用。本综述的目的是从生物学角度研究血小板，探讨血小板的生物发生及其在炎症和修复过程中的生物学作用，并从临床角度，通过血小板病理学及其在牙科再生手术中作为血小板浓缩物的应用来进行研究。
