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茶多酚:一种天然抗氧化剂,可调节肠道菌群以保护肠黏膜并预防慢性疾病。

Tea Polyphenols: A Natural Antioxidant Regulates Gut Flora to Protect the Intestinal Mucosa and Prevent Chronic Diseases.

作者信息

Wang Xinzhou, Liu Yanan, Wu Zufang, Zhang Peng, Zhang Xin

机构信息

Department of Food Science and Engineering, Ningbo University, Ningbo 315211, China.

Department of Student Affairs, Xinyang Normal University, Xinyang 464000, China.

出版信息

Antioxidants (Basel). 2022 Jan 28;11(2):253. doi: 10.3390/antiox11020253.

Abstract

The intestinal tract of a healthy human body hosts many microorganisms that are closely linked to all aspects of people's lives. The impact of intestinal flora on host health is no longer limited to the gut but can also affect every organ in the body through various pathways. Studies have found that intestinal flora can be altered by external factors, which provides new ideas for treating some diseases. Tea polyphenols (TP), a general term for polyphenols in tea, are widely used as a natural antioxidant in various bioactive foods. In recent years, with the progress of research, there have been many experiments that provide strong evidence for the ability of TP to regulate intestinal flora. However, there are very few studies on the use of TP to modify the composition of intestinal microorganisms to maintain health or treat related diseases, and this area has not received sufficient attention. In this review, we outline the mechanisms by which TP regulates intestinal flora and the essential role in maintaining suitable health. In addition, we highlighted the protective effects of TP on intestinal mucosa by regulating intestinal flora and the preventive and therapeutic effects on certain chronic diseases, which will help further explore measures to prevent related chronic diseases.

摘要

健康人体的肠道中寄生着许多微生物,它们与人们生活的方方面面紧密相连。肠道菌群对宿主健康的影响不再局限于肠道,还可通过多种途径影响身体的各个器官。研究发现,肠道菌群会受到外部因素的影响,这为某些疾病的治疗提供了新思路。茶多酚(TP)是茶叶中多酚类物质的总称,在各种生物活性食品中被广泛用作天然抗氧化剂。近年来,随着研究的进展,有许多实验为TP调节肠道菌群的能力提供了有力证据。然而,关于利用TP改变肠道微生物组成以维持健康或治疗相关疾病的研究非常少,这一领域尚未得到足够的关注。在这篇综述中,我们概述了TP调节肠道菌群的机制及其在维持适当健康方面的重要作用。此外,我们强调了TP通过调节肠道菌群对肠道黏膜的保护作用以及对某些慢性疾病的预防和治疗作用,这将有助于进一步探索预防相关慢性疾病的措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/815b/8868443/ec76553623ff/antioxidants-11-00253-g001.jpg

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