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限制热量饮食对肥胖症患者 C 反应蛋白（CRP）水平的影响：一项随机对照试验的系统评价和荟萃分析。

Effect of calorie restriction diet on levels of C reactive protein (CRP) in obesity: A systematic review and meta-analysis of randomized controlled trials.

机构信息

Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Ciptomangunkusumo National General Hospital, Jakarta, Indonesia.

Faculty of Medicine, Universitas Indonesia, Indonesia.

出版信息

Diabetes Metab Syndr. 2022 Mar;16(3):102388. doi: 10.1016/j.dsx.2022.102388. Epub 2022 Jan 5.

DOI:10.1016/j.dsx.2022.102388
PMID:35219261
Abstract

BACKGROUND AND AIMS

Chronic inflammation in obese patients can be managed through a calorie-restricted diet, characterized by reduced C - reactive protein (CRP). This study aims to assess the role of such diet on CRP.

METHODS

Literature searches were performed using search engines. Randomized controlled trials were included. Calorie-restricted diets in combination with non-diet interventions were excluded.

RESULTS

Calorie restriction decreased CRP in obese patients with a mean difference of -0.22 (95% CI -0.40 to -0.04, p 0.006).

CONCLUSIONS

Calorie-restricted diet reduces CRP. Diet administration >12 weeks had a beneficial effect.

摘要

背景和目的

肥胖患者的慢性炎症可以通过热量限制饮食来控制，这种饮食的特点是 C 反应蛋白（CRP）减少。本研究旨在评估这种饮食对 CRP 的作用。

方法

使用搜索引擎进行文献检索。纳入随机对照试验。排除热量限制饮食与非饮食干预相结合的研究。

结果

热量限制使肥胖患者的 CRP 降低，平均差值为-0.22（95%可信区间-0.40 至-0.04，p<0.006）。

结论

热量限制饮食可降低 CRP。饮食干预时间>12 周有有益效果。

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