Duchene Sebastian, Featherstone Leo, Freiesleben de Blasio Birgitte, Holmes Edward C, Bohlin Jon, Pettersson John H O
Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Department of Methods Development and Analytics, Division of Infectious Disease Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.
Open Forum Infect Dis. 2022 Jan 3;9(3):ofab665. doi: 10.1093/ofid/ofab665. eCollection 2022 Mar.
We explored how the duration, size, and number of virus transmission clusters, defined as country-specific monophyletic groups in a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) phylogenetic tree, differed among the Nordic countries of Norway, Sweden, Denmark, Finland, and Iceland. Our results suggest that although geographical connectivity, population density, and openness influence the spread and the size of SARS-CoV-2 transmission clusters, the different country-specific intervention strategies had the largest impact. We also found a significant positive association between the size and duration of transmission clusters in the Nordic countries, suggesting that the rapid deployment of contact tracing is a key response measure in reducing virus transmission.
我们探讨了病毒传播集群的持续时间、规模和数量（在严重急性呼吸综合征冠状病毒2（SARS-CoV-2）系统发育树中定义为特定国家的单系群）在挪威、瑞典、丹麦、芬兰和冰岛这几个北欧国家之间有何不同。我们的结果表明，尽管地理连通性、人口密度和开放性会影响SARS-CoV-2传播集群的传播和规模，但不同的特定国家干预策略影响最大。我们还发现北欧国家传播集群的规模和持续时间之间存在显著的正相关，这表明快速部署接触者追踪是减少病毒传播的关键应对措施。
