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使用基于自然语言处理的虚拟患者模拟器将学习分析应用于临床诊断推理:案例研究

Learning Analytics Applied to Clinical Diagnostic Reasoning Using a Natural Language Processing-Based Virtual Patient Simulator: Case Study.

作者信息

Furlan Raffaello, Gatti Mauro, Mene Roberto, Shiffer Dana, Marchiori Chiara, Giaj Levra Alessandro, Saturnino Vincenzo, Brunetta Enrico, Dipaola Franca

机构信息

Department of Biomedical Sciences, Humanitas University, Milan, Italy.

IRCCS, Humanitas Research Hospital, Rozzano, Milan, Italy.

出版信息

JMIR Med Educ. 2022 Mar 3;8(1):e24372. doi: 10.2196/24372.

DOI:10.2196/24372
PMID:35238786
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8931645/
Abstract

BACKGROUND

Virtual patient simulators (VPSs) log all users' actions, thereby enabling the creation of a multidimensional representation of students' medical knowledge. This representation can be used to create metrics providing teachers with valuable learning information.

OBJECTIVE

The aim of this study is to describe the metrics we developed to analyze the clinical diagnostic reasoning of medical students, provide examples of their application, and preliminarily validate these metrics on a class of undergraduate medical students. The metrics are computed from the data obtained through a novel VPS embedding natural language processing techniques.

METHODS

A total of 2 clinical case simulations (tests) were created to test our metrics. During each simulation, the students' step-by-step actions were logged into the program database for offline analysis. The students' performance was divided into seven dimensions: the identification of relevant information in the given clinical scenario, history taking, physical examination, medical test ordering, diagnostic hypothesis setting, binary analysis fulfillment, and final diagnosis setting. Sensitivity (percentage of relevant information found) and precision (percentage of correct actions performed) metrics were computed for each issue and combined into a harmonic mean (F), thereby obtaining a single score evaluating the students' performance. The 7 metrics were further grouped to reflect the students' capability to collect and to analyze information to obtain an overall performance score. A methodological score was computed based on the discordance between the diagnostic pathway followed by students and the reference one previously defined by the teacher. In total, 25 students attending the fifth year of the School of Medicine at Humanitas University underwent test 1, which simulated a patient with dyspnea. Test 2 dealt with abdominal pain and was attended by 36 students on a different day. For validation, we assessed the Spearman rank correlation between the performance on these scores and the score obtained by each student in the hematology curricular examination.

RESULTS

The mean overall scores were consistent between test 1 (mean 0.59, SD 0.05) and test 2 (mean 0.54, SD 0.12). For each student, the overall performance was achieved through a different contribution in collecting and analyzing information. Methodological scores highlighted discordances between the reference diagnostic pattern previously set by the teacher and the one pursued by the student. No significant correlation was found between the VPS scores and hematology examination scores.

CONCLUSIONS

Different components of the students' diagnostic process may be disentangled and quantified by appropriate metrics applied to students' actions recorded while addressing a virtual case. Such an approach may help teachers provide students with individualized feedback aimed at filling competence drawbacks and methodological inconsistencies. There was no correlation between the hematology curricular examination score and any of the proposed scores as these scores address different aspects of students' medical knowledge.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3d/8931645/d148bd1e1e3f/mededu_v8i1e24372_fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3d/8931645/1a4ded259526/mededu_v8i1e24372_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3d/8931645/cf7e7f6ac750/mededu_v8i1e24372_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3d/8931645/f2bc418dc7d4/mededu_v8i1e24372_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3d/8931645/f8ba79157dc7/mededu_v8i1e24372_fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3d/8931645/d148bd1e1e3f/mededu_v8i1e24372_fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3d/8931645/1a4ded259526/mededu_v8i1e24372_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3d/8931645/cf7e7f6ac750/mededu_v8i1e24372_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3d/8931645/f2bc418dc7d4/mededu_v8i1e24372_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3d/8931645/f8ba79157dc7/mededu_v8i1e24372_fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f3d/8931645/d148bd1e1e3f/mededu_v8i1e24372_fig5.jpg
摘要

背景

虚拟患者模拟器(VPS)会记录所有用户的操作,从而能够创建学生医学知识的多维表示。这种表示可用于创建指标,为教师提供有价值的学习信息。

目的

本研究的目的是描述我们开发的用于分析医学生临床诊断推理的指标,提供其应用示例,并在一类本科医学生中初步验证这些指标。这些指标是根据通过一种嵌入自然语言处理技术的新型VPS获得的数据计算得出的。

方法

共创建了2个临床病例模拟(测试)来测试我们的指标。在每次模拟过程中,学生的逐步操作被记录到程序数据库中以供离线分析。学生的表现分为七个维度:在给定临床场景中识别相关信息、病史采集、体格检查、医嘱检查、诊断假设设定、二元分析完成情况以及最终诊断设定。针对每个问题计算敏感性(找到的相关信息的百分比)和精确性(执行的正确操作的百分比)指标,并将其合并为调和平均数(F),从而获得一个评估学生表现的单一分数。这7个指标进一步分组以反映学生收集和分析信息以获得总体表现分数的能力。根据学生遵循的诊断路径与教师先前定义的参考路径之间的不一致性计算方法学分数。共有25名就读于胡曼itas大学医学院五年级的学生参加了测试1,该测试模拟了一名呼吸困难的患者。测试2涉及腹痛,在不同日期有36名学生参加。为了进行验证,我们评估了这些分数的表现与每个学生在血液学课程考试中获得的分数之间的Spearman等级相关性。

结果

测试1(平均0.59,标准差0.05)和测试2(平均0.54,标准差0.12)之间的平均总体分数一致。对于每个学生,总体表现是通过在收集和分析信息方面的不同贡献实现的。方法学分数突出了教师先前设定的参考诊断模式与学生遵循的诊断模式之间的不一致性。在VPS分数与血液学考试分数之间未发现显著相关性。

结论

通过应用于解决虚拟病例时记录的学生操作的适当指标,可以分解和量化学生诊断过程的不同组成部分。这种方法可能有助于教师为学生提供个性化反馈,以弥补能力缺陷和方法上的不一致性。血液学课程考试分数与任何提议的分数之间均无相关性,因为这些分数涉及学生医学知识的不同方面。

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