Nasr Muhammed Hassan, Hassan Bassam Abdul Rasool, Othman Noordin, Karuppannan Mahmathi, Abdulaziz Noorizan Binti, Mohammed Ali Haider, Alsarani Mohammed Ahmed, Eskembaji Mohammed Husain, Aman Abdelmannan Mohamed, Othman Gamil
Clinical Pharmacy Department, Faculty of Health Sciences and Nursing, Al-Rayan Colleges, Al-Madinah Al-Munawarah, Saudi Arabia.
Department of Pharmacy, Al Rafidain University College, Baghdad, 10001, Iraq.
Diabetes Metab Syndr Obes. 2022 Feb 28;15:647-657. doi: 10.2147/DMSO.S350626. eCollection 2022.
The link between the risk of type 2 diabetes mellitus (T2DM) and vitamin D deficiency has perplexed the medical society due to the controversy in the data available. Saudi Arabia (SA) is a sunny region; however, ample amount of data reported the increased prevalence of vitamin D deficiency along with T2DM. Thus, this study aimed to compare vitamin D deficiency between healthy and T2DM patients in SA, alongside with the risk factors associated with that.
A cross-sectional study was conducted in the Medical Unit, Taibah University in Al-Madinah Al-Munawarah, SA, from November 2017 to May 2018. The involved participants were non-diabetics and T2DM men. Measuring vitamin D for T2DM and non-diabetics group was done by trained technicians. Data analysis was done via SPSS.
Sixty-four participants (T2DM group = 32; non-diabetics group = 32) were recruited, and the mean age of T2DM patients was 48.6 ± 10.4, while that of the non-diabetics was 42.4 ± 6.5. The mean of vitamin D level was found higher in the non-diabetic participants than in diabetic patients. There was statistically significant association between vitamin D deficiency and T2DM ( = 0.001). Besides, duration of diabetes was the only factor, found to be positively correlated with vitamin D deficiency in T2DM patients.
Early screening for vitamin D serum-level is recommended for T2DM patients in Saudi Arabia. Therefore, early correction of vitamin D levels should be considered, and medical and scientific societies, along with other sectors such as the media, should highlight and increase the awareness of the importance of vitamin D and the seriousness of its deficiency.
2型糖尿病(T2DM)风险与维生素D缺乏之间的联系因现有数据存在争议而困扰着医学界。沙特阿拉伯(SA)是一个阳光充足的地区;然而,大量数据表明维生素D缺乏与T2DM的患病率均有所上升。因此,本研究旨在比较沙特阿拉伯健康人群与T2DM患者之间的维生素D缺乏情况,以及与之相关的风险因素。
2017年11月至2018年5月,在沙特阿拉伯麦地那穆纳瓦拉的泰巴大学医学部进行了一项横断面研究。参与研究的对象为非糖尿病男性和T2DM男性。由经过培训的技术人员对T2DM组和非糖尿病组进行维生素D检测。通过SPSS进行数据分析。
招募了64名参与者(T2DM组 = 32;非糖尿病组 = 32),T2DM患者的平均年龄为48.6±10.4岁,而非糖尿病患者的平均年龄为42.4±6.5岁。发现非糖尿病参与者的维生素D水平均值高于糖尿病患者。维生素D缺乏与T2DM之间存在统计学显著关联(P = 0.001)。此外,糖尿病病程是唯一被发现与T2DM患者维生素D缺乏呈正相关的因素。
建议对沙特阿拉伯的T2DM患者进行维生素D血清水平的早期筛查。因此,应考虑早期纠正维生素D水平,医学和科学协会以及媒体等其他部门应强调并提高对维生素D重要性及其缺乏严重性的认识。