Pradhan Swetalina, Sharma Shyama, Kumar Anup, Singh Prabhat Kumar
Department of Dermatology, All India Institute of Medical Sciences, Patna, Bihar, India.
Department of Medicine, All India Institute of Medical Sciences, Patna, Bihar, India.
J Family Med Prim Care. 2021 Dec;10(12):4598-4604. doi: 10.4103/jfmpc.jfmpc_963_21. Epub 2021 Dec 27.
The hyperinflammatory phase of COVID-19 occurring because of cytokine storm is the leading cause of mortality and morbidity in the affected patients. Various drugs with no definite cure are being tried to tackle the cytokine storm. Recently high dose corticosteroids are being used to arrest the surge of cytokines. In the current case series, we will be discussing the outcome of high dose dexamethasone pulse therapy in 10 cases of COVID-19 in hyperinflammatory phase who were cured of the disease along with improvement in laboratory parameters without any complications to the therapy.
由细胞因子风暴引起的COVID-19高炎症期是受影响患者死亡和发病的主要原因。目前正在尝试使用各种尚无明确疗效的药物来应对细胞因子风暴。最近，高剂量皮质类固醇被用于抑制细胞因子的激增。在本病例系列中，我们将讨论高剂量地塞米松脉冲疗法对10例处于高炎症期的COVID-19患者的治疗结果，这些患者均已治愈，实验室指标有所改善，且治疗无任何并发症。
