Zandieh Mohamad, Liu Juewen
Department of Chemistry, Waterloo Institute for Nanotechnology, Waterloo, Ontario N2L 3G1, Canada.
Langmuir. 2022 Mar 29;38(12):3617-3622. doi: 10.1021/acs.langmuir.2c00070. Epub 2022 Mar 15.
The field of nanozyme aims to use nanomaterials to replace protein-based enzymes. Nanozymes have attracted extensive interest because of their stability, cost-effectiveness, and versatility. While the focus of the nanozyme field has mainly been the discovery of new nanozyme materials and the exploration of their analytical, biomedical, and environmental applications, the number of fundamental studies is growing. Nanozymes are related to two important fields: enzymology and heterogeneous catalysis. Although fitting nanozyme kinetic data to the Michaelis-Menten kinetics is a very common practice, using the surface science methods of heterogeneous catalysis can provide insights about their catalytic mechanisms. The definition of a nanozyme unit is critical to understanding and comparing nanozyme activities. In this perspective, we articulate the use of a surface science approach to study nanozymes and discuss the various application scenarios of using different nanozyme units.
纳米酶领域旨在利用纳米材料替代基于蛋白质的酶。纳米酶因其稳定性、成本效益和多功能性而引起了广泛关注。虽然纳米酶领域的重点主要是新型纳米酶材料的发现及其在分析、生物医学和环境方面的应用探索，但基础研究的数量正在增加。纳米酶与两个重要领域相关：酶学和多相催化。尽管将纳米酶动力学数据拟合到米氏动力学是一种非常常见的做法，但使用多相催化的表面科学方法可以深入了解其催化机制。纳米酶单位的定义对于理解和比较纳米酶活性至关重要。从这个角度出发，我们阐述了使用表面科学方法研究纳米酶，并讨论了使用不同纳米酶单位的各种应用场景。
