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本文引用的文献

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Nutr Metab Cardiovasc Dis. 2021 Apr 9;31(4):1299-1307. doi: 10.1016/j.numecd.2020.12.002. Epub 2021 Feb 3.
2
High-sugar feeding and increasing cholesterol levels in infants.高糖喂养和增加婴儿的胆固醇水平。
Eur Heart J. 2021 Mar 21;42(12):1132-1135. doi: 10.1093/eurheartj/ehaa868.
3
Obesity risk in Hispanic children: Bidirectional associations between child eating behavior and child weight status over time.西班牙裔儿童肥胖风险:儿童饮食行为与儿童体重状况随时间的双向关联。
Eat Behav. 2020 Jan;36:101366. doi: 10.1016/j.eatbeh.2020.101366. Epub 2020 Jan 15.
4
Determinants of a dietary pattern linked with greater metabolic risk and its tracking during adolescence.与更高代谢风险相关的饮食模式的决定因素及其在青春期的变化。
J Hum Nutr Diet. 2018 Apr;31(2):218-227. doi: 10.1111/jhn.12519. Epub 2017 Oct 4.
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Clustering of Dietary Patterns, Lifestyles, and Overweight among Spanish Children and Adolescents in the ANIBES Study.西班牙儿童和青少年饮食模式、生活方式与超重情况在ANIBES研究中的聚类分析
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肥胖儿童的食物消费与低密度脂蛋白胆固醇水平升高之间的关系。

Association between food consumption and high levels of low density lipoprotein cholesterol among obese children.

机构信息

Medicine Graduation Course, Santo Amaro University, São Paulo, Brazil.

Post-graduation Program in Health Sciences, Santo Amaro University, São Paulo, Brazil.

出版信息

Pediatr Endocrinol Diabetes Metab. 2022;28(1):46-53. doi: 10.5114/pedm.2022.112864.

DOI:10.5114/pedm.2022.112864
PMID:35307996
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10226342/
Abstract

INTRODUCTION

The increase in the prevalence of obesity and obesity in children is a pattern of the last decades. This public health issue results in metabolic disorders such as dyslipidemia with increased LDL-C. Previous findings shows that most of the Brazilian children does not follow the recommended consumption of fruits and vegetables.

AIM OF THE STUDY

To evaluate the association of dietary intake characteristics with elevated serum cholesterol from low density lipoprotein in obese children.

MATERIAL AND METHODS

Cross-sectional study involving 137 obese children (5-10 years). The mean age of the studied children was 8.27 years, 55.5% were male The weight measurements were performed on a digital anthropometric scale. The body mass index was calculated for each child and the Food Frequency Questionnaire was applied. The peripheral blood was collected for lipid profile analysis. Stata 12.0 statistical package was used to analyze the data, considering a significance level of p < 0.05.

RESULTS

The prevalence of hypercholesterolemia based on the serum cholesterol from low density lipoprotein fraction was 14.6%. It was observed that children in the group who consumed the lower difference of risky and protective foods on a daily basis were not less likely to have a high cholesterol from low density lipoprotein level as a criterion for hypercholesterolemia (p = 0.218).

CONCLUSIONS

A large proportion of the individuals presented levels of lipid profile classified as undesirable for age, as well as food rich in components capable of increasing this profile, which should encourage the intensification in measures of prevention of cardiovascular diseases since childhood.

摘要

简介

肥胖和儿童肥胖症的患病率增加是过去几十年的一种趋势。这一公共卫生问题导致代谢紊乱,如 LDL-C 升高的血脂异常。先前的研究结果表明,大多数巴西儿童没有遵循推荐的水果和蔬菜摄入量。

研究目的

评估饮食摄入特征与肥胖儿童血清胆固醇升高的相关性。

材料和方法

这是一项涉及 137 名肥胖儿童(5-10 岁)的横断面研究。研究儿童的平均年龄为 8.27 岁,55.5%为男性。体重测量在数字人体测量秤上进行。为每个孩子计算了体重指数,并应用了食物频率问卷。采集外周血进行血脂谱分析。使用 Stata 12.0 统计软件包分析数据,置信水平为 p<0.05。

结果

根据低密度脂蛋白血清胆固醇,高胆固醇血症的患病率为 14.6%。观察到,每天摄入风险和保护食物差异较小的儿童,其 LDL 胆固醇水平升高的可能性并不小(p=0.218)。

结论

很大一部分个体的血脂谱水平被归类为年龄不适当,并且富含能够增加这种谱的成分的食物,这应该鼓励从儿童期开始加强心血管疾病的预防措施。