Multitherapeutic Efficacy of Curly Kale Extract Fabricated Biogenic Silver Nanoparticles.

PURPOSE

Due to the biomedical applications universally, the Ag nanoparticles are one of the most commonly investigated nanoparticles (NPs). Curly kale (BroL) leaves contain numerous beneficial nutrients and phytochemicals. The aim of the current study is the fabrication of the Ag nanoparticles using the extracts of curly kale and to investigate their biological potentials.

METHODS

The characterization of the generated BroLAgNPs was done through UV-Vis spectro study, Fourier-transform infrared spectro study, scanning electron microscope analysis, energy-dispersive X-ray study, distribution of size and zeta potential investigation, and X-ray powder diffraction study, and their biological effects were evaluated by antidiabetic, antioxidant, antibacterial and cytotoxicity effect.

RESULTS

BroL-Ag nanoparticle displayed surface plasmon resonance at 432 nm. The Zeta potential of BroL (-26.6) AgNPs displayed a highly negative charge. In antidiabetic assay, BroL-AgNPs was highly effective with IC value 2.29 µg/mL at 1.0 µg/mL concentration. In cytotoxicity assay, BroL-AgNPs displayed strong activity at 10.0 µg/mL concentration. It showed inhibitory action against three food-borne pathogenic bacteria (9.29-11.44 mm inhibition zone) and displayed moderate antioxidant potential.

CONCLUSION

This study as a whole report an eco-friendly green synthesis of AgNPs using leafy vegetable aqueous extract and its multi-biological effects which could serve as a promising candidate in pharmacological and related industries.