Department of Otorhinolaryngology-Head and Neck Surgery, The Affiliated Wuxi No. 2 People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Department of Obstetrics and Gynecology, The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
J Chin Med Assoc. 2022 May 1;85(5):597-602. doi: 10.1097/JCMA.0000000000000723. Epub 2022 May 2.
Allergic rhinitis is a frequent disorder during pregnancy, while in children it is triggered by significantly lower serum vitamin E level. This research aimed to investigate whether serum vitamin E level exhibited clinical significance in pregnant women with allergic rhinitis.
In this study, 37 pregnant women with allergic rhinitis and 35 healthy pregnant women were recruited. Allergic rhinitis severity was analyzed by the Total Nasal Symptom Score (TNSS) questionnaire. Blood samples were collected to evaluate serum vitamin E, interleukin (IL), and total IgE levels.
In pregnant women with allergic rhinitis, serum level of vitamin E was significantly lower than in healthy pregnant women. Serum vitamin E level in pregnant women with allergic rhinitis showed a negative correlation with TNSS, IL-13, IL-4, and total IgE levels.
In conclusion, this research has demonstrated that pregnant women with allergic rhinitis showed significantly lower serum level of vitamin E. The decreased vitamin E showed a correlation with the pathogenesis of allergic rhinitis in pregnant women.
过敏性鼻炎在孕期较为常见，而在儿童中，它是由血清维生素 E 水平显著降低引起的。本研究旨在探讨过敏性鼻炎孕妇的血清维生素 E 水平是否具有临床意义。
本研究纳入了 37 例过敏性鼻炎孕妇和 35 例健康孕妇。采用总鼻症状评分（TNSS）问卷分析过敏性鼻炎严重程度。采集血样评估血清维生素 E、白细胞介素（IL）和总 IgE 水平。
过敏性鼻炎孕妇的血清维生素 E 水平明显低于健康孕妇。过敏性鼻炎孕妇的血清维生素 E 水平与 TNSS、IL-13、IL-4 和总 IgE 水平呈负相关。
综上所述，本研究表明过敏性鼻炎孕妇的血清维生素 E 水平明显降低。维生素 E 的减少与孕妇过敏性鼻炎的发病机制有关。
