饮食与干预对多发性硬化症的作用：综述
The Role of Diet and Interventions on Multiple Sclerosis: A Review.
机构信息
2nd Department of Neurology, AHEPA Hospital, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
出版信息
Nutrients. 2022 Mar 9;14(6):1150. doi: 10.3390/nu14061150.
Abstract
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) characterized by inflammation and neurodegeneration. The most prominent clinical features include visual loss and sensorimotor symptoms and mainly affects those of young age. Some of the factors affecting its pathogenesis are genetic and/or environmental including viruses, smoking, obesity, and nutrition. Current research provides evidence that diet may influence MS onset, course, and quality of life of the patients. In this review, we address the role of nutrition on MS pathogenesis as well as dietary interventions that show promising beneficial results with respect to MS activity and progression. Investigation with large prospective clinical studies is required in order to thoroughly evaluate the role of diet in MS.
摘要
多发性硬化症（MS）是一种中枢神经系统（CNS）的慢性自身免疫性疾病，其特征是炎症和神经退行性变。最突出的临床特征包括视力丧失和感觉运动症状，主要影响年轻人。影响其发病机制的一些因素包括遗传和/或环境因素，包括病毒、吸烟、肥胖和营养。目前的研究提供了证据表明，饮食可能会影响 MS 的发病、病程和患者的生活质量。在这篇综述中，我们探讨了营养在 MS 发病机制中的作用，以及在 MS 活动和进展方面显示出有希望的有益结果的饮食干预措施。需要进行大型前瞻性临床研究，以全面评估饮食在 MS 中的作用。
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