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使用 BCG 或脉搏波信号的 HRV 分析一致性的统计分析。

Statistical Analysis of the Consistency of HRV Analysis Using BCG or Pulse Wave Signals.

机构信息

College of Medicine and Biological and Information Engineering, Northeastern University, Shenyang 110167, China.

Philips Design, 5611 AZ Eindhoven, The Netherlands.

出版信息

Sensors (Basel). 2022 Mar 21;22(6):2423. doi: 10.3390/s22062423.

DOI:10.3390/s22062423
PMID:35336592
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8951337/
Abstract

Ballistocardiography (BCG) is considered a good alternative to HRV analysis with its non-contact and unobtrusive acquisition characteristics. However, consensus about its validity has not yet been established. In this study, 50 healthy subjects (26.2 ± 5.5 years old, 22 females, 28 males) were invited. Comprehensive statistical analysis, including Coefficients of Variation (CV), Lin’s Concordance Correlation Coefficient (LCCC), and Bland-Altman analysis (BA ratio), were utilized to analyze the consistency of BCG and ECG signals in HRV analysis. If the methods gave different answers, the worst case was taken as the result. Measures of consistency such as Mean, SDNN, LF gave good agreement (the absolute value of CV difference < 2%, LCCC > 0.99, BA ratio < 0.1) between J-J (BCG) and R-R intervals (ECG). pNN50 showed moderate agreement (the absolute value of CV difference < 5%, LCCC > 0.95, BA ratio < 0.2), while RMSSD, HF, LF/HF indicated poor agreement (the absolute value of CV difference ≥ 5% or LCCC ≤ 0.95 or BA ratio ≥ 0.2). Additionally, the R-R intervals were compared with P-P intervals extracted from the pulse wave (PW). Except for pNN50, which exhibited poor agreement in this comparison, the performances of the HRV indices estimated from the PW and the BCG signals were similar.

摘要

心冲击图（BCG）具有非接触式和非侵入式的采集特点，被认为是心率变异性（HRV）分析的良好替代方法。然而，其有效性尚未达成共识。在这项研究中，邀请了 50 名健康受试者（26.2±5.5 岁，22 名女性，28 名男性）。综合统计分析，包括变异系数（CV）、Lin 的一致性相关系数（LCCC）和 Bland-Altman 分析（BA 比），用于分析 BCG 和 ECG 信号在 HRV 分析中的一致性。如果两种方法给出了不同的答案，则取最坏情况作为结果。如果一致性度量（如 Mean、SDNN、LF）的 CV 差值绝对值<2%，LCCC>0.99，BA 比<0.1，则 J-J（BCG）和 R-R 间隔（ECG）之间具有良好的一致性。pNN50 表现出中等一致性（CV 差值绝对值<5%，LCCC>0.95，BA 比<0.2），而 RMSSD、HF、LF/HF 则表现出较差的一致性（CV 差值绝对值≥5%或 LCCC≤0.95 或 BA 比≥0.2）。此外，还将 R-R 间隔与从脉搏波（PW）中提取的 P-P 间隔进行了比较。除了 pNN50 在这种比较中表现出较差的一致性外，从 PW 和 BCG 信号中估计的 HRV 指数的性能相似。

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