辉瑞-BioNTech 新冠肺炎疫苗接种后单纯疱疹性前部葡萄膜炎：两例病例报告。
Herpetic anterior uveitis following Pfizer-BioNTech coronavirus disease 2019 vaccine: two case reports.
机构信息
Ophthalmology Department, Complejo Hospitalario Universitario de Albacete, Albacete, Spain.
Ophthalmology Department, Hospital General Universitario Reina Sofía de Murcia, Murcia, Spain.
出版信息
J Med Case Rep. 2022 Mar 25;16(1):127. doi: 10.1186/s13256-022-03350-6.
PURPOSE
To describe two cases of herpetic anterior uveitis after inoculation of the first dose of Pfizer-BioNTech coronavirus disease 2019 vaccine.
METHODS
Case 1: a healthy 92-year-old Caucasian woman developed symptomatic unilateral anterior uveitis for 3 days after Pfizer-BioNTech coronavirus disease 2019 vaccination (Pfizer Inc.). The episode fully resolved with topical and oral antiviral treatment. Case 2: a previously healthy 85-year-old Caucasian woman with left hemicranial signs of herpes zoster infection, associated with herpetic keratouveitis for 3 days after Pfizer-BioNTech coronavirus disease 2019 vaccination. Treatment with topical antibiotics and both oral and topical antiherpetic medication was administered, and she recovered successfully in 5 weeks.
CONCLUSION
Clinicians should be aware of the possibility of eye inflammation in the form of herpetic reactivation after coronavirus disease 2019 vaccination.
目的
描述两例接种辉瑞-生物科技公司 COVID-19 疫苗第一针后发生疱疹性前葡萄膜炎的病例。
方法
病例 1：一名健康的 92 岁白人女性，在接种辉瑞-生物科技公司 COVID-19 疫苗（辉瑞公司）后 3 天出现单侧症状性前葡萄膜炎。经局部和口服抗病毒治疗后完全缓解。病例 2：一名既往健康的 85 岁白人女性，左侧半头出现带状疱疹感染的迹象，与接种辉瑞-生物科技公司 COVID-19 疫苗后 3 天发生的疱疹性角膜葡萄膜炎相关。给予局部抗生素和口服及局部抗疱疹药物治疗，5 周后成功康复。
结论
临床医生应意识到 COVID-19 疫苗接种后可能出现疱疹再激活形式的眼部炎症。
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