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新冠疫情第一波期间及之前的剖宫产率与结局

Cesarean section rate and outcomes during and before the first wave of COVID-19 pandemic.

作者信息

Eleje George Uchenna, Ugwu Emmanuel Onyebuchi, Enebe Joseph Tochukwu, Okoro Chukwuemeka Chukwubuikem, Okpala Boniface Chukwuneme, Ezeora Nnanyelugo Chima, Iloghalu Emeka Ifeanyi, Anikwe Chidebe Christian, Okafor Chigozie Geoffrey, Agu Polycarp Uchenna, Igbodike Emeka Philip, Ake Iffiyeosuo Dennis, Ekwuazi Kingsley Emeka, Onwuegbuna Arinze Anthony, Umeononihu Osita Samuel, Anaedu Onyedika Promise, Ikwuka David Chibuike, Nwaolisa Henry Ifeanyi, Njoku Chukwuemeka Chidindu, Nwankwo Chidinma Patricia, Emeka Ekene Agatha, Eleje Lydia Ijeoma, Adinnu Kenechi Miracle, Okoye Chinelo Onuegbuna, Ugwu Angela Ogechukwu, Nwachukwu Ethel Oluchukwu, Mba Sunday Gabriel, Ezenkwele Eziamaka Pauline, Okoye Uchenna Elizabeth, Ofiaeli Chika Ifeoma, Ikpeze Golibe Christian, Onah Livinus Nnanyere, Ikpeze Odigonma Zinobia, Ejikeme Toochukwu Benjamin, Udigwe Gerald Okanandu, Ikechebelu Joseph Ifeanyichukwu

机构信息

Effective Care Research Unit, Department of Obstetrics and Gynecology, Nnamdi Azikiwe University, Awka, Nigeria.

Department of Obstetrics and Gynecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.

出版信息

SAGE Open Med. 2022 Mar 23;10:20503121221085453. doi: 10.1177/20503121221085453. eCollection 2022.

Abstract

OBJECTIVES

The objective of the study was to assess how the current COVID-19 pandemic has affected cesarean section (C-section) rates, indications, and peripartum outcomes.

METHODS

This was a retrospective cross-sectional study that compared a 3-month rates of and indications for C-sections at three tertiary health care institutions in Nigeria before (October 2019-December 2019) and during the first wave of COVID-19 pandemic (March 2020-May 2020). Primary outcomes were C-section rate and indications between the two periods. Data were analyzed using SPSS 26.0 IBM Corporation. Rates and odds ratios with 95% confidence intervals were used to quantify indications and peripartum outcomes and statistical significance was accepted when p value was <0.05.

RESULTS

The baseline characteristics of the two groups were similar. The C-section rate during the COVID-19 period was significantly less than the period prior to the pandemic (237/580, 40.0% vs 390/833, 46.8%; p = 0.027). The rates of postdatism (odds ratio = 1.47, 95% confidence interval = 1.05-2.05, p = 0.022), fetal distress (odds ratio = 3.06, 95% confidence interval = 1.55-6.06, p = 0.017), emergency C-section (odds ratio = 1.43, 95% confidence interval = 1.01-2.05, p = 0.042), and anemia (odds ratio = 1.84, 95% confidence interval = 1.12-3.03, p = 0.016) were significantly higher during the pandemic than prepandemic.

CONCLUSION

The overall C-section rate during the first wave of COVID-19 was significantly lower than the prepandemic period. There were higher rates of postdatism, fetal distress, emergency C-section, and postpartum anemia. Further studies on this changing C-section trend during the pandemic are needed.

摘要

目的

本研究的目的是评估当前的新冠疫情如何影响剖宫产率、剖宫产指征及围产期结局。

方法

这是一项回顾性横断面研究,比较了尼日利亚三家三级医疗机构在新冠疫情第一波之前(2019年10月至2019年12月)和期间(2020年3月至2020年5月)三个月内的剖宫产率及指征。主要结局是两个时期的剖宫产率和指征。使用IBM公司的SPSS 26.0软件进行数据分析。采用95%置信区间的率和比值比来量化指征和围产期结局,当p值<0.05时接受统计学显著性。

结果

两组的基线特征相似。新冠疫情期间的剖宫产率显著低于疫情前时期(237/580,40.0%对390/833,46.8%;p = 0.027)。过期妊娠(比值比 = 1.47,95%置信区间 = 1.05 - 2.05,p = 0.022)、胎儿窘迫(比值比 = 3.06,95%置信区间 = 1.55 - 6.06,p = 0.017)、急诊剖宫产(比值比 = 1.43,95%置信区间 = 1.01 - 2.05,p = 0.042)和贫血(比值比 = 1.84,95%置信区间 = 1.12 - 3.03,p = 0.016)的发生率在疫情期间显著高于疫情前。

结论

新冠疫情第一波期间的总体剖宫产率显著低于疫情前时期。过期妊娠、胎儿窘迫、急诊剖宫产和产后贫血的发生率更高。需要对疫情期间这种不断变化的剖宫产趋势进行进一步研究。

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