Filippi Courtney A, Valadez Emilio A, Fox Nathan A, Pine Daniel S
Emotion and Development Branch, National Institute of Mental Health, Bethesda, MD, 20892, United States.
Department of Human Development and Quantitative Methodology, University of Maryland, College Park, MD, 20742, United States.
Curr Opin Behav Sci. 2022 Apr;44. doi: 10.1016/j.cobeha.2022.101105. Epub 2022 Feb 24.
Behavioral inhibition (BI), an infant temperament characterized by distress to novelty, is amongst the strongest early risk markers for future anxiety. In this review, we highlight three ways that recent research elucidates key details about the pathophysiology of anxiety in individuals with BI. First, atypical amygdala connectivity during infancy may be related to BI. Second, developmental shifts in cognitive control may portend risk for anxiety for children with BI. Lastly, distinct cognitive control processes moderate the BI-anxiety relation in different ways. Studying the intersection of these three streams of work may inform prevention or intervention work.
行为抑制（BI）是一种婴儿气质类型，其特征为对新事物感到苦恼，是未来焦虑最强的早期风险指标之一。在本综述中，我们强调了近期研究阐明BI个体焦虑症病理生理学关键细节的三种方式。首先，婴儿期杏仁核连接异常可能与BI有关。其次，认知控制的发展变化可能预示着BI儿童患焦虑症的风险。最后，不同的认知控制过程以不同方式调节BI与焦虑之间的关系。研究这三个研究方向的交叉点可能为预防或干预工作提供信息。
