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俄罗斯联邦的 EQ-5D-3L 的首个群体常模。

First population norms for the EQ-5D-3L in the Russian Federation.

机构信息

International Centre for Health Economics, Management and Policy, National Research University Higher School of Economics, St. Petersburg, Russian Federation.

Oxford School of Global and Area Studies, University of Oxford, Oxford, England.

出版信息

PLoS One. 2022 Mar 29;17(3):e0263816. doi: 10.1371/journal.pone.0263816. eCollection 2022.

Abstract

PURPOSE

The EQ-5D survey instrument is routinely applied to general and patient specific populations in many countries, as a means of measuring Health Related Quality of Life (HRQOL) and/or informing Health Technology Assessment. The instrument is the subject of growing interest in the Russian Federation, as too is Health Technology Assessment. This research is the first to systematically present the EQ-5D-3L nationally representative population norms and to examine the socioeconomic and socio-demographic characteristics of the instrument among a representative sample of the Russian population.

METHODS

Based on a nationally representative health and well-being survey of the Russian population, conducted in November 2017, we establish the descriptive results, including the EQ-VAS and the EQ-5D Index, by age and gender, examine the correspondence between the EQ-5D health classifications and the separate EQ-VAS scores, and draw on a set of augmented logistic regressions to evaluate the association between the presence of problems in each dimension and various socio-economic and health-related characteristics.

RESULTS

We find strong evidence that the EQ-5D instrument is sensitive to underlying observed and latent health experiences, that it mirrors many of the characteristics familiar from other settings but that there are Russian specificities which merit further research, particularly with respect to the anxiety/depression dimension of the instrument.

CONCLUSION

This research represents an important landmark for HRQOL studies in Russia as well as for the prospects of continuing to develop the scholarly and practical infrastructure necessary for Russian Health Technology Assessment to advance.

摘要

目的

EQ-5D 调查工具在许多国家的一般人群和特定患者群体中被常规应用,作为衡量健康相关生活质量(HRQOL)和/或为健康技术评估提供信息的手段。该工具在俄罗斯联邦越来越受到关注,健康技术评估也是如此。这项研究首次系统地呈现了 EQ-5D-3L 在全国范围内具有代表性的人群标准,并在俄罗斯代表性人群样本中检查了该工具的社会经济和社会人口统计学特征。

方法

基于 2017 年 11 月进行的一项全国性的俄罗斯人口健康和幸福感调查,我们根据年龄和性别确定了描述性结果,包括 EQ-VAS 和 EQ-5D 指数,检查了 EQ-5D 健康分类与单独的 EQ-VAS 评分之间的对应关系,并利用一组增强型逻辑回归来评估每个维度存在问题与各种社会经济和健康相关特征之间的关联。

结果

我们有强有力的证据表明,EQ-5D 工具对潜在的观察到的和潜在的健康体验敏感,它反映了许多其他环境中熟悉的特征,但也存在俄罗斯特有的特征,值得进一步研究,特别是对于该工具的焦虑/抑郁维度。

结论

这项研究代表了俄罗斯 HRQOL 研究以及继续发展俄罗斯健康技术评估所需的学术和实践基础设施的重要里程碑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8def/8963536/7ad08f8d083c/pone.0263816.g001.jpg

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