阑尾切除术后的经皮电神经刺激：安慰剂效应。
Transcutaneous electrical nerve stimulation following appendicectomy: the placebo effect.
作者信息
Conn I G, Marshall A H, Yadav S N, Daly J C, Jaffer M
出版信息
Ann R Coll Surg Engl. 1986 Jul;68(4):191-2.
Abstract
A controlled trial was undertaken to compare the efficacy of transcutaneous electrical nerve stimulation (TENS) with standard intramuscular opiate analgesia in the management of postoperative pain following appendicectomy. Consecutive patients undergoing emergency appendicectomy were randomised into control, sham TENS and active TENS groups. There was a significant decrease in pain severity and analgesic intake in both active and sham TENS groups when compared with the control group (P less than 0.01). No difference was demonstrated in pain severity between active and sham TENS groups but the active TENS group required slightly less analgesia. These results suggest that the major benefit of TENS in the postappendicectomy patient is due to its 'placebo effect' and its use in this situation cannot be recommended.
摘要
进行了一项对照试验，比较经皮电神经刺激（TENS）与标准肌肉注射阿片类镇痛在阑尾切除术后疼痛管理中的疗效。连续接受急诊阑尾切除术的患者被随机分为对照组、假TENS组和活性TENS组。与对照组相比，活性TENS组和假TENS组的疼痛严重程度和镇痛药物摄入量均显著降低（P小于0.01）。活性TENS组和假TENS组在疼痛严重程度上没有差异，但活性TENS组所需的镇痛药物略少。这些结果表明，TENS对阑尾切除术后患者的主要益处归因于其“安慰剂效应”，因此不建议在这种情况下使用。
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本文引用的文献
1
The perception of pain.
Sci Am. 1961 Feb;204:41-9. doi: 10.1038/scientificamerican0261-41.
2
Treatment of osteoarthritis of the knee with transcutaneous electrical nerve stimulation.
Pain. 1981 Oct;11(2):233-240. doi: 10.1016/0304-3959(81)90008-7.
3
The effect of transcutaneous electric nerve stimulation on postoperative pain and pulmonary function.
Surgery. 1981 Apr;89(4):507-12.
4
Respiratory effects of analgesia after cholecystectomy: comparison of continuous and intermittent papaveretum.胆囊切除术后镇痛的呼吸效应：持续与间断应用罂粟碱的比较
Br Med J. 1980 Aug 16;281(6238):478-80. doi: 10.1136/bmj.281.6238.478.
5
Pain mechanisms: a new theory.疼痛机制：一种新理论。
Science. 1965 Nov 19;150(3699):971-9. doi: 10.1126/science.150.3699.971.
6
Transcutaneous electrical stimulation for postoperative pain.经皮电刺激用于术后疼痛治疗。
Ann R Coll Surg Engl. 1985 Mar;67(2):127-9.
7
Pethidine revisited: plasma concentrations and effects after intramuscular injection.哌替啶再探讨：肌内注射后的血药浓度及效应
Br J Anaesth. 1975 Dec;47(12):1269-75. doi: 10.1093/bja/47.12.1269.
8
Use of transcutaneous electrical stimulation in the control of postoperative pain.经皮电刺激在术后疼痛控制中的应用。
Am J Surg. 1977 Feb;133(2):185-7. doi: 10.1016/0002-9610(77)90077-0.
9
Prolonged relief of pain by brief, intense transcutaneous somatic stimulation.通过短暂、强烈的经皮躯体刺激实现疼痛的长期缓解。
Pain. 1975 Dec;1(4):357-373. doi: 10.1016/0304-3959(75)90073-1.
10
Narcotic analgesics and delayed gastric emptying during labour.
Lancet. 1975 Apr 19;1(7912):890-3. doi: 10.1016/s0140-6736(75)91687-6.
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