Sheng Manjin, Xu Wenjie, Yang Jane, Chen Zhongjie
School of Informatics, Xiamen University, Xiamen, China.
Department of Cognitive Science, University of California, San Diego, San Diego, CA, United States.
Front Neurosci. 2022 Mar 22;16:836412. doi: 10.3389/fnins.2022.836412. eCollection 2022.
Stroke is an acute cerebrovascular disease with high incidence, high mortality, and high disability rate. Determining the location and volume of the disease in MR images promotes accurate stroke diagnosis and surgical planning. Therefore, the automatic recognition and segmentation of stroke lesions has important clinical significance for large-scale stroke imaging analysis. There are some problems in the segmentation of stroke lesions, such as imbalance of the front and back scenes, uncertainty of position, and unclear boundary. To meet this challenge, this paper proposes a cross-attention and deep supervision UNet (CADS-UNet) to segment chronic stroke lesions from T1-weighted MR images. Specifically, we propose a cross-spatial attention module, which is different from the usual self-attention module. The location information interactively selects encode features and decode features to enrich the lost spatial focus. At the same time, the channel attention mechanism is used to screen the channel characteristics. Finally, combined with deep supervision and mixed loss, the model is supervised more accurately. We compared and verified the model on the authoritative open dataset "Anatomical Tracings of Lesions After Stroke" (Atlas), which fully proved the effectiveness of our model.
中风是一种发病率高、死亡率高、致残率高的急性脑血管疾病。在磁共振成像(MR)图像中确定疾病的位置和体积有助于准确的中风诊断和手术规划。因此,中风病变的自动识别和分割对于大规模中风成像分析具有重要的临床意义。中风病变的分割存在一些问题,如前后场景不平衡、位置不确定和边界不清晰。为应对这一挑战,本文提出了一种交叉注意力和深度监督的U型网络(CADS-UNet),用于从T1加权MR图像中分割慢性中风病变。具体来说,我们提出了一种交叉空间注意力模块,它不同于通常的自注意力模块。位置信息交互式地选择编码特征和解码特征,以丰富丢失的空间焦点。同时,利用通道注意力机制筛选通道特征。最后,结合深度监督和混合损失,对模型进行更精确的监督。我们在权威的开放数据集“中风后病变的解剖追踪”(Atlas)上对模型进行了比较和验证,充分证明了我们模型的有效性。