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Lipidomic risk scores are independent of polygenic risk scores and can predict incidence of diabetes and cardiovascular disease in a large population cohort.脂质组学风险评分独立于多基因风险评分,可以预测大型人群队列中糖尿病和心血管疾病的发病风险。
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2
The foundations and development of lipidomics.脂质组学的基础与发展。
J Lipid Res. 2022 Feb;63(2):100164. doi: 10.1016/j.jlr.2021.100164. Epub 2021 Dec 22.
3
Recommendations for good practice in MS-based lipidomics.基于 MS 的脂质组学实践建议。
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4
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脂质组学在疾病预测中的新兴作用。

The emerging role of lipidomics in prediction of diseases.

机构信息

Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Division of Diabetes, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

出版信息

Nat Rev Endocrinol. 2022 Jun;18(6):335-336. doi: 10.1038/s41574-022-00672-9.

DOI:10.1038/s41574-022-00672-9
PMID:35393579
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10151196/
Abstract

A recent paper published in reported the application of lipidomics in predicting the incidence of diabetes and cardiovascular diseases in a population cohort. The study is clearly remarkable in demonstrating the role of lipidomics in prediction of diseases and translational research. We believe it comes to an era with quantitative lipidomics.

摘要

最近发表的一篇论文报道了脂质组学在人群队列中预测糖尿病和心血管疾病发病率中的应用。该研究在展示脂质组学在疾病预测和转化研究中的作用方面显然是显著的。我们相信这是一个定量脂质组学的时代。