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碱土硅酸盐、纳米离子体和玻璃离子修复材料长期氟释放及抗菌活性的比较评价——一项研究。

Comparative evaluation of long-term fluoride release and antibacterial activity of an alkasite, nanoionomer, and glass ionomer restorative material - An study.

作者信息

Aparajitha R V, Selvan P Senthamil, Ahamed A Shafie, Bhavani S, Nagarajan V

机构信息

Department of Conservative Dentistry and Endodontics, Rajah Muthiah Dental College and Hospital, Annamalai University, Chidambaram, Tamil Nadu, India.

出版信息

J Conserv Dent. 2021 Sep-Oct;24(5):485-490. doi: 10.4103/jcd.jcd_336_21. Epub 2022 Mar 7.

DOI:10.4103/jcd.jcd_336_21
PMID:35399765
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8989179/
Abstract

BACKGROUND

The antibacterial activity of restorative material and the amount of fluoride released are interlinked. Hence, these are the two foremost properties to be studied.

AIM

This study aimed to evaluate and compare the amount and pattern of fluoride release from Type IX GIC (GC HS posterior), nanoionomer (Ketac N100), and alkasite (Cention N), and the antibacterial activity against at 24 and 48 h.

SETTINGS AND DESIGN

This study was carried out in laboratory settings with six samples of each group for fluoride release using an ion-chromatography (IC) machine and five samples of each group for antibacterial activity using agar plates.

MATERIALS AND METHODOLOGY

Samples of each group, Group I - Type IX GIC, Group II - nanoionomer, and Group III -alkasite, were prepared, immersed in 2 ml of artificial saliva, and fluoride release recorded using IC after 1, 7, 14, and 28 days intervals. The antibacterial activity against was evaluated by placing samples of each group in the agar plates and measuring the diameter of zones of inhibition after 24 and 48 h.

STATISTICAL ANALYSIS

One-way ANOVA test to check to mean differences between the groups and Tukey's honestly significant difference test for multiple intergroup comparisons ( = 0.05).

RESULTS

The Type IX GIC showed the highest fluoride release after day1. However, nanoionomer showed the maximum fluoride release for the remaining days. The least amount of fluoride released was from the alkasite throughout the study. The antibacterial activity of nanoionomer was the highest, followed by Type IX GIC and alkasite at both 24 and 48 h.

CONCLUSIONS

Nanoionomer showed the highest fluoride release and antibacterial activity.

摘要

背景

修复材料的抗菌活性与氟释放量相互关联。因此，这是两个需要重点研究的特性。

目的

本研究旨在评估并比较IX型玻璃离子水门汀（GC HS后牙型）、纳米离子体（Ketac N100）和碱式玻璃离子（Cention N）的氟释放量及释放模式，以及它们在24小时和48小时时的抗菌活性。

设置与设计

本研究在实验室环境中进行，每组使用六个样本通过离子色谱仪检测氟释放量，每组使用五个样本通过琼脂平板检测抗菌活性。

材料与方法

制备每组样本，即第一组 - IX型玻璃离子水门汀、第二组 - 纳米离子体、第三组 - 碱式玻璃离子，将其浸入2毫升人工唾液中，分别在1天、7天、14天和28天后使用离子色谱仪记录氟释放量。通过将每组样本置于琼脂平板中，测量24小时和48小时后抑菌圈的直径来评估其对[具体细菌名称未给出]的抗菌活性。

统计分析

采用单因素方差分析检验组间均值差异，并使用Tukey's真实显著性差异检验进行多组间比较（α = 0.05）。

结果

IX型玻璃离子水门汀在第1天后氟释放量最高。然而，在其余时间纳米离子体的氟释放量最大。在整个研究过程中，碱式玻璃离子的氟释放量最少。纳米离子体在24小时和48小时时的抗菌活性最高，其次是IX型玻璃离子水门汀和碱式玻璃离子。

结论

纳米离子体显示出最高的氟释放量和抗菌活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2731/8989179/948575d2fdc8/JCD-24-485-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2731/8989179/84a7d2707c8f/JCD-24-485-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2731/8989179/af2d9e8dc1ed/JCD-24-485-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2731/8989179/e6b1d19cefd8/JCD-24-485-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2731/8989179/b25811cc27d0/JCD-24-485-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2731/8989179/355fd34d8e35/JCD-24-485-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2731/8989179/948575d2fdc8/JCD-24-485-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2731/8989179/84a7d2707c8f/JCD-24-485-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2731/8989179/af2d9e8dc1ed/JCD-24-485-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2731/8989179/e6b1d19cefd8/JCD-24-485-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2731/8989179/b25811cc27d0/JCD-24-485-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2731/8989179/355fd34d8e35/JCD-24-485-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2731/8989179/948575d2fdc8/JCD-24-485-g006.jpg

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