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“组学”技术如何推动植物工程、生态系统监测、人类和动物健康。

How 'omics technologies can drive plant engineering, ecosystem surveillance, human and animal health.

机构信息

La Trobe Institute for Agriculture and Food, La Trobe University, AgriBio Building, Bundoora, VIC 3086, Australia.

Australian Research Council Research Hub for Medicinal Agriculture, La Trobe University, AgriBio Building, Bundoora, VIC 3086, Australia.

出版信息

Emerg Top Life Sci. 2022 Apr 15;6(2):137-139. doi: 10.1042/ETLS20220020.

Abstract

'Omics describes a broad collection of research tools and techniques that enable researchers to collect data about biological systems at a very large, or near-complete, scale. These include sequencing of individual and community genomes (genomics, metagenomics), characterization and quantification of gene expression (transcriptomics), metabolite abundance (metabolomics), protein content (proteomics) and phosphorylation (phospho-proteomics), amongst many others. Though initially exploited as tools for fundamental discovery, 'omics techniques are now used extensively in applied and translational research, for example in plant and animal breeding, biomarker development and drug discovery. In this collection of reviews, we aimed to introduce readers to current and future applications of 'omics technologies to solve real-world problems.

摘要

“组学”描述了一系列广泛的研究工具和技术,使研究人员能够大规模或近乎完整地收集有关生物系统的数据。这些包括个体和群落基因组的测序(基因组学、宏基因组学)、基因表达的特征和定量(转录组学)、代谢物丰度(代谢组学)、蛋白质含量(蛋白质组学)和磷酸化(磷酸化蛋白质组学)等。尽管最初被用作基础发现的工具,但“组学”技术现在已广泛应用于应用和转化研究,例如在动植物育种、生物标志物开发和药物发现中。在本综述集中,我们旨在向读者介绍“组学”技术的当前和未来应用,以解决实际问题。

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本文引用的文献

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Genome analyses reveal the hybrid origin of the staple crop white Guinea yam ().基因组分析揭示了主食白木薯()的杂种起源。
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The barley pan-genome reveals the hidden legacy of mutation breeding.大麦泛基因组揭示了诱变育种的隐藏遗产。
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