Tagnaout Imane, Zerkani Hannou, Hadi Nadia, El Moumen Bouchra, El Makhoukhi Fadoua, Bouhrim Mohamed, Al-Salahi Rashad, Nasr Fahd A, Mechchate Hamza, Zair Touriya
Research Team of Chemistry of Bioactive Molecules and the Environment, Laboratory of Innovative Materials and Biotechnology of Natural Resources, Faculty of Sciences, Moulay Ismaïl University, B.P. 11201 Zitoune, Meknes 50070, Morocco.
Laboratoire Centre Eau, Ressources Naturelles, Environnement Et Développement Durable, Faculty of Sciences, University Mohammed V, Rabat B.P. 8007, Rabat 10000, Morocco.
Plants (Basel). 2022 Mar 31;11(7):954. doi: 10.3390/plants11070954.
and are two Moroccan endemic medicinal plants used traditionally by the local population. The present study aims to investigate their essential oil chemical composition, antioxidant and antibacterial activities. The chemical composition of the essential oils was determined using the GC-MS analysis, the antioxidant activity assessed using DPPH and FRAP methods while the antimicrobial activity was evaluated against nine bacteria species tested (, , , , sensitive , sensitive , resistant , resistant and ). The major identified compounds of essential oil where carvacrol (75%) and -cymene (10.58%) while carvacrol (60.79%), thymol (12.9%), -cymene (6.21%) and -terpinene (4.47%) are the main compounds in essential oil. The bioactivity of the essential oils of the two species of thyme was explained by their richness in oxygenated monoterpenes known for their great effectiveness with an IC of 3.48 ± 0.05 and 4.88 ± 0.04 μL/mL and EC of 0.12 ± 0.01 and 0.20 ± 0.02 μL/mL in the DPPH and FRAP assays, respectively, with an important antibacterial activity. These results encourage the use of these plants as a source of natural antioxidants, and antibacterial additives, to protect food from oxidative damage and to eliminate bacteria that are responsible for nosocomial infections.
[植物名称1]和[植物名称2]是摩洛哥特有的两种药用植物，当地居民传统上一直在使用。本研究旨在调查它们的精油化学成分、抗氧化和抗菌活性。采用气相色谱-质谱联用（GC-MS）分析法测定精油的化学成分，用二苯基苦味酰基自由基（DPPH）和铁离子还原抗氧化能力（FRAP）方法评估抗氧化活性，同时针对九种测试细菌（[细菌名称1]、[细菌名称2]、[细菌名称3]、[细菌名称4]、敏感的[细菌名称5]、敏感的[细菌名称6]、耐药的[细菌名称7]、耐药的[细菌名称8]和[细菌名称9]）评估抗菌活性。[植物名称1]精油中鉴定出的主要化合物是香芹酚（75%）和对伞花烃（10.58%），而[植物名称2]精油中的主要化合物是香芹酚（60.79%）、百里香酚（12.9%）、对伞花烃（6.21%）和γ-萜品烯（4.47%）。这两种百里香属植物精油的生物活性归因于其富含氧化单萜，这些氧化单萜具有很高的功效，在DPPH和FRAP试验中的半数抑制浓度（IC）分别为3.48±0.05和4.88±0.04μL/mL，有效浓度（EC）分别为0.12±0.01和0.20±0.02μL/mL，同时具有重要的抗菌活性。这些结果促使人们将这些植物用作天然抗氧化剂和抗菌添加剂的来源，以保护食品免受氧化损伤，并消除导致医院感染的细菌。
