Kamanina Olga A, Saverina Evgeniya A, Rybochkin Pavel V, Arlyapov Vyacheslav A, Vereshchagin Anatoly N, Ananikov Valentine P
Tula State University, Lenin pr. 92, 300012 Tula, Russia.
N. D. Zelinsky Institute of Organic Chemistry, Leninsky pr. 47, 119991 Moscow, Russia.
Nanomaterials (Basel). 2022 Mar 25;12(7):1086. doi: 10.3390/nano12071086.
Microorganism-cell-based biohybrid materials have attracted considerable attention over the last several decades. They are applied in a broad spectrum of areas, such as nanotechnologies, environmental biotechnology, biomedicine, synthetic chemistry, and bioelectronics. Sol-gel technology allows us to obtain a wide range of high-purity materials from nanopowders to thin-film coatings with high efficiency and low cost, which makes it one of the preferred techniques for creating organic-inorganic matrices for biocomponent immobilization. This review focuses on the synthesis and application of hybrid sol-gel materials obtained by encapsulation of microorganism cells in an inorganic matrix based on silicon, aluminum, and transition metals. The type of immobilized cells, precursors used, types of nanomaterials obtained, and their practical applications were analyzed in detail. In addition, techniques for increasing the microorganism effective time of functioning and the possibility of using sol-gel hybrid materials in catalysis are discussed.
在过去几十年中，基于微生物细胞的生物杂交材料引起了广泛关注。它们被应用于广泛的领域，如纳米技术、环境生物技术、生物医学、合成化学和生物电子学。溶胶-凝胶技术使我们能够以高效率和低成本获得从纳米粉末到薄膜涂层的各种高纯度材料，这使其成为制备用于生物组分固定化的有机-无机基质的首选技术之一。本综述重点关注通过将微生物细胞封装在基于硅、铝和过渡金属的无机基质中获得的杂化溶胶-凝胶材料的合成与应用。详细分析了固定化细胞的类型、所用前驱体、获得的纳米材料类型及其实际应用。此外，还讨论了延长微生物有效功能时间的技术以及在催化中使用溶胶-凝胶杂化材料的可能性。
