• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Evaluating ribosomal frameshifting in CCR5 mRNA decoding.

作者信息

Khan Yousuf A, Loughran Gary, Steckelberg Anna-Lena, Brown Katherine, Kiniry Stephen J, Stewart Hazel, Baranov Pavel V, Kieft Jeffrey S, Firth Andrew E, Atkins John F

机构信息

Division of Virology, Department of Pathology, University of Cambridge, Cambridge, UK.

Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA.

出版信息

Nature. 2022 Apr;604(7906):E16-E23. doi: 10.1038/s41586-022-04627-y. Epub 2022 Apr 20.

DOI:10.1038/s41586-022-04627-y
PMID:35444316
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9248028/
Abstract
摘要

相似文献

1
Evaluating ribosomal frameshifting in CCR5 mRNA decoding.评估CCR5 mRNA解码过程中的核糖体移码。
Nature. 2022 Apr;604(7906):E16-E23. doi: 10.1038/s41586-022-04627-y. Epub 2022 Apr 20.
2
The energy landscape of -1 ribosomal frameshifting.-1 核糖体移码的能量景观。
Sci Adv. 2020 Jan 1;6(1):eaax6969. doi: 10.1126/sciadv.aax6969. eCollection 2020 Jan.
3
Ribosomal frameshifting in the CCR5 mRNA is regulated by miRNAs and the NMD pathway.核糖体移码在 CCR5 mRNA 中受 miRNA 和 NMD 途径的调控。
Nature. 2014 Aug 21;512(7514):265-9. doi: 10.1038/nature13429. Epub 2014 Jul 9.
4
Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.EF-G 催化转位过程中+1 核糖体移码的结构基础。
Nat Commun. 2021 Jul 30;12(1):4644. doi: 10.1038/s41467-021-24911-1.
5
Ribosome collisions alter frameshifting at translational reprogramming motifs in bacterial mRNAs.核糖体碰撞改变细菌 mRNA 中转译重编程基序的框架移位。
Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21769-21779. doi: 10.1073/pnas.1910613116. Epub 2019 Oct 7.
6
A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting.RNA假结在程序性核糖体移码中功能的机械学解释
Nature. 2006 May 11;441(7090):244-7. doi: 10.1038/nature04735.
7
A novel role for poly(C) binding proteins in programmed ribosomal frameshifting.聚(C)结合蛋白在程序性核糖体移码中的新作用。
Nucleic Acids Res. 2016 Jul 8;44(12):5491-503. doi: 10.1093/nar/gkw480. Epub 2016 Jun 2.
8
Changed in translation: mRNA recoding by -1 programmed ribosomal frameshifting.翻译变更:通过-1程序性核糖体移码进行mRNA重编码。
Trends Biochem Sci. 2015 May;40(5):265-74. doi: 10.1016/j.tibs.2015.03.006. Epub 2015 Apr 4.
9
Characterization of the stimulators of protein-directed ribosomal frameshifting in Theiler's murine encephalomyelitis virus.鉴定 Theiler 氏鼠脑脊髓炎病毒中蛋白指导的核糖体移码的刺激因子。
Nucleic Acids Res. 2019 Sep 5;47(15):8207-8223. doi: 10.1093/nar/gkz503.
10
Lack of evidence for ribosomal frameshifting in ATP7B mRNA decoding.缺乏 ATP7B mRNA 解码中核糖体移码的证据。
Mol Cell. 2022 Oct 6;82(19):3745-3749.e2. doi: 10.1016/j.molcel.2022.08.024. Epub 2022 Sep 16.

引用本文的文献

1
The dual luciferase assay does not support claims of stop codon readthrough on the AGO1 mRNA.双荧光素酶测定不支持AGO1信使核糖核酸上存在终止密码子通读的说法。
EMBO J. 2025 Jun 11. doi: 10.1038/s44318-025-00478-1.
2
Structural switching dynamically controls the doubly pseudoknotted Rous sarcoma virus-programmed ribosomal frameshifting element.结构转换动态控制双假结罗氏肉瘤病毒编程的核糖体移码元件。
Proc Natl Acad Sci U S A. 2025 Apr 8;122(14):e2418418122. doi: 10.1073/pnas.2418418122. Epub 2025 Apr 2.
3
Guidelines for minimal reporting requirements, design and interpretation of experiments involving the use of eukaryotic dual gene expression reporters (MINDR).

本文引用的文献

1
Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.冠状病毒科(Coronaviridae)的结构与功能
Science. 2021 Jun 18;372(6548):1306-1313. doi: 10.1126/science.abf3546. Epub 2021 May 13.
2
Functional and structural characterization of the chikungunya virus translational recoding signals.基孔肯雅病毒翻译重编码信号的功能和结构特征。
J Biol Chem. 2018 Nov 9;293(45):17536-17545. doi: 10.1074/jbc.RA118.005606. Epub 2018 Sep 21.
3
Trips-Viz: a transcriptome browser for exploring Ribo-Seq data.
涉及真核双基因表达报告基因实验的最低报告要求、设计与解释指南(MINDR)
Nat Struct Mol Biol. 2025 Mar;32(3):418-430. doi: 10.1038/s41594-025-01492-x. Epub 2025 Mar 3.
4
RNA elements required for the high efficiency of West Nile virus-induced ribosomal frameshifting.西尼罗河病毒诱导核糖体移码高效发生所需的RNA元件。
Nucleic Acids Res. 2025 Jan 24;53(3). doi: 10.1093/nar/gkae1248.
5
Ribosomal frameshifting selectively modulates the assembly, function, and pharmacological rescue of a misfolded CFTR variant.核糖体移码选择性地调节折叠错误的 CFTR 变体的组装、功能和药理学挽救。
Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e2414768121. doi: 10.1073/pnas.2414768121. Epub 2024 Oct 10.
6
Programmed ribosomal frameshifting during mRNA decoding generates a constitutively active proteoform that supports myocardial function.mRNA解码过程中的程序性核糖体移码产生一种组成性激活的蛋白质变体,该变体支持心肌功能。
bioRxiv. 2025 Jan 14:2024.08.30.610563. doi: 10.1101/2024.08.30.610563.
7
Evolution of Virus-like Features and Intrinsically Disordered Regions in Retrotransposon-derived Mammalian Genes.逆转座子衍生的哺乳动物基因中病毒样特征和固有无序区的进化。
Mol Biol Evol. 2024 Aug 2;41(8). doi: 10.1093/molbev/msae154.
8
Ribosomal Frameshifting Selectively Modulates the Assembly, Function, and Pharmacological Rescue of a Misfolded CFTR Variant.核糖体移码选择性地调节错误折叠的囊性纤维化跨膜传导调节因子(CFTR)变体的组装、功能和药理学挽救。
bioRxiv. 2024 Jul 23:2023.05.02.539166. doi: 10.1101/2023.05.02.539166.
9
A system of reporters for comparative investigation of EJC-independent and EJC-enhanced nonsense-mediated mRNA decay.一个用于比较 EJC 非依赖性和 EJC 增强的无意义介导的 mRNA 衰减的报告者系统。
Nucleic Acids Res. 2024 Apr 12;52(6):e34. doi: 10.1093/nar/gkae121.
10
The Deficiency of Hypusinated eIF5A Decreases the Putrescine/Spermidine Ratio and Inhibits +1 Programmed Ribosomal Frameshifting during the Translation of Ty1 Retrotransposon in .eIF5A Hypusination 缺陷降低腐胺/精胺比并抑制 Ty1 逆转座子翻译中的 +1 核糖体移码
Int J Mol Sci. 2024 Feb 1;25(3):1766. doi: 10.3390/ijms25031766.
Trips-Viz:一个转录组浏览器,用于探索 Ribo-Seq 数据。
Nucleic Acids Res. 2019 Jan 8;47(D1):D847-D852. doi: 10.1093/nar/gky842.
4
GWIPS-viz: 2018 update.GWIPS-viz:2018 更新版。
Nucleic Acids Res. 2018 Jan 4;46(D1):D823-D830. doi: 10.1093/nar/gkx790.
5
Avoidance of reporter assay distortions from fused dual reporters.避免融合双报告基因导致的报告基因检测失真。
RNA. 2017 Aug;23(8):1285-1289. doi: 10.1261/rna.061051.117. Epub 2017 Apr 25.
6
Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use.核糖体移码和转录滑动:从基因隐写术和密码学到偶然用途。
Nucleic Acids Res. 2016 Sep 6;44(15):7007-78. doi: 10.1093/nar/gkw530. Epub 2016 Jul 19.
7
Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation.美国国立生物技术信息中心的参考序列(RefSeq)数据库:当前状态、分类扩展及功能注释。
Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45. doi: 10.1093/nar/gkv1189. Epub 2015 Nov 8.
8
Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation.干扰素-γ调节细胞代谢和mRNA翻译以增强巨噬细胞活化。
Nat Immunol. 2015 Aug;16(8):838-849. doi: 10.1038/ni.3205. Epub 2015 Jun 29.
9
Cell cycle control (and more) by programmed -1 ribosomal frameshifting: implications for disease and therapeutics.通过程序性 -1 核糖体移码进行细胞周期控制(及更多方面):对疾病和治疗的影响
Cell Cycle. 2015;14(2):172-8. doi: 10.4161/15384101.2014.989123.
10
Ribosomal frameshifting in the CCR5 mRNA is regulated by miRNAs and the NMD pathway.核糖体移码在 CCR5 mRNA 中受 miRNA 和 NMD 途径的调控。
Nature. 2014 Aug 21;512(7514):265-9. doi: 10.1038/nature13429. Epub 2014 Jul 9.