Kibret Anteneh Ayelign, Aragie Hailu, Belay Daniel Gashaneh, Molla Meseret Derbew, Teferi Ephrem Tafesse, Melese Endalkachew Belayneh, Worku Yilkal Belete, Wolde Haileab Fekadu, Adugna Dagnew Getnet
Department of Human Anatomy, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
J Multidiscip Healthc. 2022 Apr 14;15:793-803. doi: 10.2147/JMDH.S352114. eCollection 2022.
Hypertension is the most common comorbidities in adult cancer patients. Although hypertension is a leading cause of cancer-related death and disability, there is no evidence about its prevalence and associated factors among cancer patients in Ethiopia. Therefore, this study aimed to assess the prevalence and associated factors of hypertension among cancer patients.
Hospital-based cross-sectional study was conducted among cancer patients from January to March 2021. A systematic random sampling technique was performed to select 403 study participants. To collect the data, structured interviewer-administered questionnaires were used. Both bi-variable and multivariable binary logistic regression analyses were used to identify factors associated with hypertension. In the multivariable logistic regression analysis, adjusted odds ratios (AOR) with 95% confidence interval (CI) and P-value of less than 0.05 were used to determine significant factors.
The final result was based on 384 cancer patients. In this study, the prevalence of hypertension among adult cancer patients was 36.2% [95% CI: (31.5, 41.2)]. In the multivariable logistic regression analysis, age greater than 57 years [AOR = 5.0; 95% CI (1.7, 14.9)] and having a family history of hypertension [AOR 10.9; 95% CI (5.5, 21.6)] were found to be significantly associated with hypertension.
The prevalence of hypertension among cancer patients was considerably high. Age >57 years and family history of hypertension were found to increase the odds of having hypertension among cancer patients. Therefore, it is important to emphasize cancer patients that are at high risk of hypertension and develop preventive strategies to decrease the burden of this disease. There is a need for routine screening for hypertension for those having a positive family history of hypertension and older age, as they have an increased likelihood of developing high blood pressure among cancer patients.
高血压是成年癌症患者中最常见的合并症。尽管高血压是癌症相关死亡和残疾的主要原因，但在埃塞俄比亚的癌症患者中，尚无关于其患病率及相关因素的证据。因此，本研究旨在评估癌症患者中高血压的患病率及相关因素。
2021年1月至3月对癌症患者开展了一项基于医院的横断面研究。采用系统随机抽样技术选取403名研究参与者。通过使用结构化访谈问卷来收集数据。采用双变量和多变量二元逻辑回归分析来确定与高血压相关的因素。在多变量逻辑回归分析中，使用调整后的比值比（AOR）、95%置信区间（CI）以及小于0.05的P值来确定显著因素。
最终结果基于384名癌症患者。在本研究中，成年癌症患者中高血压的患病率为36.2% [95% CI：(31.5, 41.2)]。在多变量逻辑回归分析中，发现年龄大于57岁 [AOR = 5.0；95% CI (1.7, 14.9)] 和有高血压家族史 [AOR 10.9；95% CI (5.5, 21.6)] 与高血压显著相关。
癌症患者中高血压的患病率相当高。发现年龄>57岁和有高血压家族史会增加癌症患者患高血压的几率。因此，强调高血压高危的癌症患者并制定预防策略以减轻该疾病的负担很重要。对于有高血压家族史和年龄较大的患者，有必要进行高血压的常规筛查，因为他们在癌症患者中患高血压的可能性增加。
