ElObeid Tahra, Awad Marwa Osman, Ganji Vijay, Moawad Joyce
Human Nutrition Department, College of Health Sciences, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Department of Northern Region Operations, Primary Health Care Corporation, Doha P.O. Box 26555, Qatar.
Metabolites. 2022 Apr 8;12(4):338. doi: 10.3390/metabo12040338.
Polycystic ovary syndrome (PCOS) is an endocrinopathy that is common among women of reproductive age. It is a heterogeneous disorder with an unknown etiology. Different strategies have been proposed for the treatment of PCOS. Recent studies recommend supplementation with specific minerals for treating various PCOS phenotypes. We searched PubMed, Google Scholar, and SCOPUS databases by using search terms combining PCOS with the supplementation of magnesium, zinc, selenium, or chromium. This review presents a narrative concerning the association between PCOS and magnesium, zinc, selenium, and chromium supplementation. We review findings from various randomized controlled trials and meta-analyses conducted in women of childbearing age with PCOS. Recent reports highlight the beneficial effect of minerals on the clinical and metabolic symptoms of PCOS. Further studies are required to establish the appropriate dosage level of these minerals for ameliorating the pathologies associated with PCOS because of the potential health risks linked with higher doses.
多囊卵巢综合征（PCOS）是一种在育龄女性中常见的内分泌疾病。它是一种病因不明的异质性疾病。针对PCOS的治疗已经提出了不同的策略。最近的研究建议补充特定矿物质来治疗各种PCOS表型。我们通过使用将PCOS与镁、锌、硒或铬补充剂相结合的搜索词，在PubMed、谷歌学术和SCOPUS数据库中进行了检索。本综述阐述了有关PCOS与镁、锌、硒和铬补充剂之间关联的叙述。我们回顾了在育龄PCOS女性中进行的各种随机对照试验和荟萃分析的结果。最近的报告强调了矿物质对PCOS临床和代谢症状的有益作用。由于高剂量矿物质存在潜在健康风险，因此需要进一步研究来确定这些矿物质改善与PCOS相关病理状况的合适剂量水平。
