Yang Juan, Liao Yuting, Hua Qianhui, Lv Huakun
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, Xiamen University, Xiamen 361102, China.
School of Medicine, Ningbo University, Ningbo 315211, China.
Vaccines (Basel). 2022 Mar 28;10(4):524. doi: 10.3390/vaccines10040524.
New vaccines are being developed in response to the coronavirus disease 2019 (COVID-19) pandemic. Vaccination provides a crucial preventive approach for managing COVID-19. We investigated adults' willingness to take COVID-19 vaccines in the Zhejiang province, and their cognitions regarding COVID-19, when the COVID-19 vaccine is authorized under Emergency Use Administration. An online survey was conducted from September to October 2020, which included social-demographic characteristics, risk perception, acceptance and influencing factors in relation to COVID-19 vaccines. Multivariate logistic regression was performed to identify the influencing factors of vaccination acceptance. Of the participants, 70% intended to be vaccinated when the COVID-19 vaccine was approved under Emergency Use Administration, among 2171 valid questionnaires. Logistic regression revealed that being male, having a high cognitive score regarding COVID-19, the belief that the COVID-19 vaccine is safe and effective, and the belief that one will be infected with SARS-CoV-2 this fall and winter, were associated with a greater probability of accepting vaccination. Respondents with junior college/university education or above were less likely to accept vaccination. Concerns about the safety and effectiveness of the vaccine were the main factors hindering vaccination acceptance. Health education is important for promoting accurate public knowledge regarding COVID-19 vaccination.
针对2019冠状病毒病（COVID-19）大流行，正在研发新型疫苗。接种疫苗是应对COVID-19的关键预防措施。我们调查了浙江省成年人在COVID-19疫苗获得紧急使用授权时接种该疫苗的意愿，以及他们对COVID-19的认知情况。于2020年9月至10月进行了一项在线调查，内容包括社会人口统计学特征、风险认知、对COVID-19疫苗的接受情况及影响因素。采用多因素logistic回归分析确定接种接受度的影响因素。在2171份有效问卷中，70%的参与者表示当COVID-19疫苗获得紧急使用授权时打算接种。logistic回归分析显示，男性、对COVID-19认知得分高、认为COVID-19疫苗安全有效、以及认为自己在今冬会感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2），与接受接种的可能性更大相关。大专及以上学历的受访者接受接种的可能性较小。对疫苗安全性和有效性的担忧是阻碍接种接受度的主要因素。健康教育对于促进公众对COVID-19疫苗的准确认识很重要。
