Modrák Marcel, Trebuňová Marianna, Balogová Alena Findrik, Hudák Radovan, Živčák Jozef
Department of Biomedical Engineering and Measurement, Faculty of Mechanical Engineering, Technical University of Košice, 042 00 Košice, Slovakia.
J Funct Biomater. 2023 Mar 16;14(3):159. doi: 10.3390/jfb14030159.
The goal of this review is to map the current state of biodegradable materials that are used in tissue engineering for a variety of applications. At the beginning, the paper briefly identifies typical clinical indications in orthopedics for the use of biodegradable implants. Subsequently, the most frequent groups of biodegradable materials are identified, classified, and analyzed. To this end, a bibliometric analysis was applied to evaluate the evolution of the scientific literature in selected topics of the subject. The special focus of this study is on polymeric biodegradable materials that have been widely used for tissue engineering and regenerative medicine. Moreover, to outline current research trends and future research directions in this area, selected smart biodegradable materials are characterized, categorized, and discussed. Finally, pertinent conclusions regarding the applicability of biodegradable materials are drawn and recommendations for future research are suggested to drive this line of research forward.
本综述的目的是梳理用于组织工程各种应用的可生物降解材料的当前状况。首先，本文简要确定了骨科中使用可生物降解植入物的典型临床适应症。随后，确定、分类并分析了最常见的可生物降解材料类别。为此，应用文献计量分析来评估该学科选定主题的科学文献演变。本研究的特别重点是已广泛用于组织工程和再生医学的聚合物可生物降解材料。此外，为了概述该领域当前的研究趋势和未来研究方向，对选定的智能可生物降解材料进行了表征、分类和讨论。最后，得出关于可生物降解材料适用性的相关结论，并提出未来研究建议，以推动这一研究方向的发展。
