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病毒和细菌的光学捕获与操纵

Optical trapping and manipulation of viruses and bacteria.

作者信息

Ashkin A, Dziedzic J M

出版信息

Science. 1987 Mar 20;235(4795):1517-20. doi: 10.1126/science.3547653.

Abstract

Optical trapping and manipulation of viruses and bacteria by laser radiation pressure were demonstrated with single-beam gradient traps. Individual tobacco mosaic viruses and dense oriented arrays of viruses were trapped in aqueous solution with no apparent damage using approximately 120 milliwatts of argon laser power. Trapping and manipulation of single live motile bacteria and Escherichia coli bacteria were also demonstrated in a high-resolution microscope at powers of a few milliwatts.

摘要

利用单光束梯度阱通过激光辐射压力对病毒和细菌进行光镊捕获和操控得到了证实。使用约120毫瓦的氩激光功率,单个烟草花叶病毒和密集排列的病毒阵列在水溶液中被捕获,且没有明显损伤。在高分辨率显微镜下,以几毫瓦的功率也实现了对单个活的运动细菌和大肠杆菌的捕获与操控。

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