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玉米醇溶蛋白作为一种多功能生物聚合物:用于不同生物医学应用的不同形状。

Zein as a versatile biopolymer: different shapes for different biomedical applications.

作者信息

Tortorella Silvia, Maturi Mirko, Vetri Buratti Veronica, Vozzolo Giulia, Locatelli Erica, Sambri Letizia, Comes Franchini Mauro

机构信息

Department of Industrial Chemistry "Toso Montanari", Alma Mater Studiorum - University of Bologna Viale Risorgimento 4 40136 Bologna Italy

Istituto per l'Endocrinologia e l'Oncologia Sperimentale "G. Salvatore" (IEOS), Consiglio Nazionale delle Ricerche (CNR) Via S. Pansini 5 80131 Naples Italy.

出版信息

RSC Adv. 2021 Dec 6;11(62):39004-39026. doi: 10.1039/d1ra07424e.

Abstract

In recent years, the interest regarding the use of proteins as renewable resources has deeply intensified. The strongest impact of these biomaterials is clear in the field of smart medicines and biomedical engineering. Zein, a vegetal protein extracted from corn, is a suitable biomaterial for all the above-mentioned purposes due to its biodegradability and biocompatibility. The controlled drug delivery of small molecules, fabrication of bioactive membranes, and 3D assembly of scaffold for tissue regeneration are just some of the topics now being extensively investigated and reported in the literature. Herein, we review the recent literature on zein as a biopolymer and its applications in the biomedical world, focusing on the different shapes and sizes through which it can be manipulated.

摘要

近年来,人们对将蛋白质用作可再生资源的兴趣急剧增强。这些生物材料在智能药物和生物医学工程领域的影响最为显著。玉米醇溶蛋白是一种从玉米中提取的植物蛋白,由于其生物可降解性和生物相容性,它是用于上述所有目的的合适生物材料。小分子的可控药物递送、生物活性膜的制备以及用于组织再生的支架的三维组装,只是目前文献中广泛研究和报道的部分主题。在此,我们综述了近期关于玉米醇溶蛋白作为生物聚合物及其在生物医学领域应用的文献,重点关注其可被操控的不同形状和尺寸。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e9e/9044754/35b4dea075ea/d1ra07424e-f1.jpg

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