Mobed Ahmad, Hasanzadeh Mohammad, Seidi Farzad
Aging Research Institute, Faculty of Medicine, Tabriz University of Medical Sciences Iran
Physical Medicine and Rehabilitation Research Center, Tabriz University of Medical Sciences Tabriz Iran.
RSC Adv. 2021 Oct 26;11(55):34688-34698. doi: 10.1039/d1ra06030a. eCollection 2021 Oct 25.
Gold nanocomposites are being widely used in numerous biomedical applications owing to their excellent stability and miniaturization. Gold nanocomposites are notable because of their flexibility of functionalization and synthesis, ease of detection, and low toxicity. Cost-effectiveness, long-term stability, non-cytotoxicity, and biocompatibility are the main aspects of ideal nanocomposites. Antibacterial nanocomposites are being developed extensively in the food industry, environmental applications, and biological and medical devices. This review focuses on the applications of metal-based nanoparticles, mainly gold nanoparticles (AuNPs), as antibacterial agents in medical approaches. Additionally, the antibacterial mechanisms of AuNPs and their roles in fighting antibiotic-resistant microorganisms are highlighted in the present review.
由于具有出色的稳定性和小型化特性,金纳米复合材料正在众多生物医学应用中得到广泛使用。金纳米复合材料因其功能化和合成的灵活性、易于检测以及低毒性而备受关注。成本效益、长期稳定性、无细胞毒性和生物相容性是理想纳米复合材料的主要方面。抗菌纳米复合材料正在食品工业、环境应用以及生物和医疗设备中得到广泛开发。本综述重点关注金属基纳米颗粒,主要是金纳米颗粒(AuNPs)在医学方法中作为抗菌剂的应用。此外,本综述还强调了AuNPs的抗菌机制及其在对抗抗生素耐药微生物中的作用。