• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

念珠菌形态对两性霉素B敏感性的影响。

Effect of Candida morphology on amphotericin B susceptibility.

作者信息

Nugent K M, Couchot K R, Gray L D

出版信息

Antimicrob Agents Chemother. 1987 Feb;31(2):335-6. doi: 10.1128/AAC.31.2.335.

DOI:10.1128/AAC.31.2.335
PMID:3551836
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC174720/
Abstract

We showed that brief exposures to amphotericin B (AmB) inhibited the induction of new Candida germ tubes and the lengthening of partially induced germ tubes. Blastoconidia with germ tubes were more susceptible to AmB killing, and this varied directly with the induction period and the AmB exposure period. AmB did not preferentially affect germ tube adherence to fibrin matrices.

摘要

我们发现，短暂暴露于两性霉素B（AmB）可抑制新型念珠菌芽管的诱导以及部分诱导芽管的延长。带有芽管的芽生孢子对AmB杀伤更敏感，且这种敏感性与诱导期和AmB暴露期直接相关。AmB对芽管与纤维蛋白基质的黏附没有优先影响。

相似文献

1
Effect of Candida morphology on amphotericin B susceptibility.念珠菌形态对两性霉素B敏感性的影响。
Antimicrob Agents Chemother. 1987 Feb;31(2):335-6. doi: 10.1128/AAC.31.2.335.
2
Effects of sublethal concentrations of amphotericin B on Candida albicans.
J Infect Dis. 1986 Oct;154(4):665-9. doi: 10.1093/infdis/154.4.665.
3
Effect of amphotericin B, fluconazole and itraconazole on intracellular Candida albicans and germ tube development in macrophages.两性霉素B、氟康唑和伊曲康唑对巨噬细胞内白色念珠菌及芽管发育的影响
J Antimicrob Chemother. 1990 May;25(5):803-11. doi: 10.1093/jac/25.5.803.
4
Strong correlation between the antifungal effect of amphotericin B and its inhibitory action on germ-tube formation in a Candida albicans URA⁺ strain.两性霉素B的抗真菌作用与其对白色念珠菌URA⁺菌株芽管形成的抑制作用之间存在强相关性。
Int Microbiol. 2015 Mar;18(1):25-31. doi: 10.2436/20.1501.01.231.
5
Stable phenotypic resistance of Candida species to amphotericin B conferred by preexposure to subinhibitory levels of azoles.念珠菌属对两性霉素B的稳定表型耐药性由预先暴露于亚抑菌水平的唑类药物所致。
J Clin Microbiol. 1998 Sep;36(9):2690-5. doi: 10.1128/JCM.36.9.2690-2695.1998.
6
Comparative susceptibility of Candida albicans to amphotericin B and amphotericin B methyl ester.白色念珠菌对两性霉素B和两性霉素B甲酯的敏感性比较。
Antimicrob Agents Chemother. 1977 Oct;12(4):449-50. doi: 10.1128/AAC.12.4.449.
7
Interactions of liposomal amphotericin B with extracellular and intracellular Candida albicans.脂质体两性霉素B与细胞外和细胞内白色念珠菌的相互作用。
J Antimicrob Chemother. 1995 Dec;36(6):961-74. doi: 10.1093/jac/36.6.961.
8
Amphotericin B-induced oxidative damage and killing of Candida albicans.两性霉素B诱导的氧化损伤及对白色念珠菌的杀伤作用。
J Infect Dis. 1986 Jul;154(1):76-83. doi: 10.1093/infdis/154.1.76.
9
Conditions affecting the amphotericin B mediated inhibition of Candida albicans attachment to cell cultures.影响两性霉素B介导的白色念珠菌黏附细胞培养物的条件。
Can J Microbiol. 1989 Feb;35(2):260-4. doi: 10.1139/m89-039.
10
Intrinsic in vitro susceptibility of primary clinical isolates of Aspergillus fumigatus, Aspergillus terreus, Aspergillus nidulans, Candida albicans and Candida lusitaniae against amphotericin B.烟曲霉、土曲霉、构巢曲霉、白色念珠菌和葡萄牙念珠菌的原发性临床分离株对两性霉素B的固有体外敏感性。
Mycoses. 2006 Mar;49(2):96-103. doi: 10.1111/j.1439-0507.2006.01197.x.

引用本文的文献

1
Biological and Physico-Chemical Characteristics of Arginine-Rich Peptide Gemini Surfactants with Lysine and Cystine Spacers.富含精氨酸的肽型双子表面活性剂的赖氨酸和胱氨酸间隔基的生物和物理化学特性。
Int J Mol Sci. 2021 Mar 24;22(7):3299. doi: 10.3390/ijms22073299.
2
Action of chlorhexidine digluconate against yeast and filamentous forms in an early-stage Candida albicans biofilm.葡萄糖酸氯己定对早期白色念珠菌生物膜中酵母和丝状形态的作用
Antimicrob Agents Chemother. 2002 Nov;46(11):3522-31. doi: 10.1128/AAC.46.11.3522-3531.2002.
3
Effects of amphotericin B and fluconazole on the extracellular and intracellular growth of Candida albicans.两性霉素B和氟康唑对白色念珠菌细胞外和细胞内生长的影响。
Antimicrob Agents Chemother. 1991 Nov;35(11):2275-81. doi: 10.1128/AAC.35.11.2275.
4
Modulation of interactions of Candida albicans and endothelial cells by fluconazole and amphotericin B.氟康唑和两性霉素B对白色念珠菌与内皮细胞相互作用的调节作用
Antimicrob Agents Chemother. 1992 Oct;36(10):2239-44. doi: 10.1128/AAC.36.10.2239.

本文引用的文献

1
Zinc and regulation of growth and phenotype in the infectious yeast Candida albicans.锌与感染性酵母白色念珠菌的生长及表型调控
Infect Immun. 1981 Jun;32(3):1139-47. doi: 10.1128/iai.32.3.1139-1147.1981.
2
Influence of extracellular K+ or Mg2+ on the stages of the antifungal effects of amphotericin B and filipin.细胞外钾离子或镁离子对两性霉素B和菲律宾菌素抗真菌作用阶段的影响。
Antimicrob Agents Chemother. 1980 Oct;18(4):593-7. doi: 10.1128/AAC.18.4.593.
3
Adherence of Candida albicans to a fibrin-platelet matrix formed in vitro.白色念珠菌对体外形成的纤维蛋白 - 血小板基质的黏附。
Infect Immun. 1980 Feb;27(2):650-6. doi: 10.1128/iai.27.2.650-656.1980.
4
Effects of amphotericin B, nystatin, and other polyene antibiotics on chitin synthase.两性霉素B、制霉菌素及其他多烯类抗生素对几丁质合酶的作用。
Proc Natl Acad Sci U S A. 1981 Feb;78(2):1233-6. doi: 10.1073/pnas.78.2.1233.
5
Inhibitory effects of chlorpromazine on Candida species.氯丙嗪对念珠菌属的抑制作用。
Antimicrob Agents Chemother. 1985 May;27(5):692-4. doi: 10.1128/AAC.27.5.692.
6
Involvement of oxidative damage in erythrocyte lysis induced by amphotericin B.氧化损伤在两性霉素B诱导的红细胞裂解中的作用。
Antimicrob Agents Chemother. 1985 Feb;27(2):172-6. doi: 10.1128/AAC.27.2.172.
7
Temporal and spatial differences in cell wall expansion during bud and mycelium formation in Candida albicans.白色念珠菌芽体和菌丝体形成过程中细胞壁扩张的时空差异。
J Gen Microbiol. 1985 Jun;131(6):1467-80. doi: 10.1099/00221287-131-6-1467.
8
Factors governing adherence of Candida species to plastic surfaces.影响念珠菌属在塑料表面黏附的因素。
Infect Immun. 1985 Oct;50(1):97-101. doi: 10.1128/iai.50.1.97-101.1985.
9
Germ tube-forming cells of Candida albicans are more susceptible to clotrimazole-induced killing than yeast cells.白色念珠菌的芽管形成细胞比酵母细胞对克霉唑诱导的杀伤更敏感。
Sabouraudia. 1985 Feb;23(1):63-8.
10
Effects of sublethal concentrations of amphotericin B on Candida albicans.
J Infect Dis. 1986 Oct;154(4):665-9. doi: 10.1093/infdis/154.4.665.