Department of Cancer Genetics with Cytogenetic Laboratory, Medical University of Lublin, Lublin, Poland.
Department of Obstetrics and Pathology of Pregnancy, Medical University of Lublin, Lublin, Poland.
Ann Med. 2022 Dec;54(1):1350-1356. doi: 10.1080/07853890.2022.2071459.
MicroRNAs (miRNAs) are a class of small non-coding, single-stranded RNAs (ribonucleic acids) that play important roles in many vital processes through their impact on gene expression. One such miRNA, miR210, represents a hypoxia-induced cellular miRNA group that hold a variety of functions. This review article highlights the importance of miR-210 in the development of pre-eclampsia.KEY MESSAGEmiR-210 is a promising biomarker for monitoring pregnancy with pre-eclampsia. Overexpression of miR-210 had a negative impact on the process of cell migration and trophoblast invasion.
微小 RNA（miRNAs）是一类小的非编码、单链 RNA（核糖核酸），通过影响基因表达，在许多重要的生命过程中发挥重要作用。miR210 是一种缺氧诱导的细胞 miRNA 群，具有多种功能。本文综述了 miR210 在子痫前期发生发展中的重要作用。
关键信息miR210 是一种有前途的生物标志物，可用于监测子痫前期的妊娠情况。miR210 的过表达对细胞迁移和滋养细胞侵袭过程有负面影响。
