Basler A, von der Hude W, Scheutwinkel M
Food Chem Toxicol. 1987 Apr;25(4):287-90. doi: 10.1016/0278-6915(87)90124-4.
Genotoxic properties of the food additive propionic acid were analysed using the Escherichia coli DNA repair assay, the SOS chromotest, the Salmonella/microsome mutagenicity test, the sister chromatid exchange test in vitro and the micronucleus test in vivo. All tests except the DNA repair assay with E. coli yielded negative results. These data support other evidence that propionic acid is not mutagenic and that genotoxic events are unlikely to be the cause of forestomach lesions in rats fed propionic acid in the diet (Griem, Bundesgesundheitsblatt 1985, 28, 322).
使用大肠杆菌DNA修复试验、SOS显色试验、沙门氏菌/微粒体诱变性试验、体外姐妹染色单体交换试验和体内微核试验分析了食品添加剂丙酸的遗传毒性特性。除大肠杆菌DNA修复试验外，所有试验均得出阴性结果。这些数据支持了其他证据，即丙酸没有致突变性，并且遗传毒性事件不太可能是饮食中摄入丙酸的大鼠前胃损伤的原因（格里姆，《联邦卫生报》1985年，第28卷，第322页）。
